MIP-1α Expression Induced by Co-Stimulation of Human Monocytic Cells with Palmitate and TNF-α Involves the TLR4-IRF3 Pathway and Is Amplified by Oxidative Stress

MIP-1α Expression Induced by Co-Stimulation of Human Monocytic Cells with Palmitate and TNF-α Involves the TLR4-IRF3 Pathway and Is Amplified by Oxidative Stress

Metabolic inflammation is associated with increased expression of a saturated free fatty acid, proinflammatory cytokines, chemokines, and adipose oxidative stress. Macrophage inflammatory protein (MIP) -1α recruit inflammatory cells such as monocytes, macrophages, and neutrophils in adipose tissue; However, the mechanism of promoting the expression of MIP-1α remains unclear.

We hypothesized that the co-induced by palmitate and tumor necrosis factor (TNF) -α in monocytic cells / macrophages can be further enhanced by the presence of reactive oxygen species (ROS) -mediated oxidative stress MIP-1α. To investigate this, THP-1 cells monocytic and human macrophages primary co-stimulated by palmitate and TNF-α and mRNA and protein levels of MIP-1α was measured by using transcription quantitative reverse, polymerase chain reaction (qRT-PCR) and commercial tests enzyme -linked immunosorbent assay (ELISA), respectively.

Cognate receptors of palmitic, pulses like receptor (TLR) -4, was blunted by genetic ablation, neutralization, and chemical inhibition. The involvement of TLR4-downstream pathway, interferon regulatory factor (IRF) -3 or myeloid differentiation (MYD) -88 factors, determined by using IRF3-siRNA or MyD88-deficient cells. induced oxidative stress in cells by hydrogen peroxide (H2O2) and ROS induction treatment was measured with dichloro-dihydro-fluorescein diacetate (DCFH-DA) assay. Data show that MIP-1α gene expression / protein upregulated in cells co-stimulated by palmitate / TNF-α compared with those stimulated with either palmitic or TNF-α (P <0.05).

Furthermore, TLR4-IRF3 the pathway involved in cooperative induction of MIP-1α in THP-1 cells, and this kooperatititas between palmitate and TNF-α is a clathrin-dependent and is also required signal through the c-Jun and nuclear factor kappa-light- to medium-chain enhancer activated B cells (NF-kB). In particular, the ROS itself induced MIP-1α and could further promote the secretion of MIP-1α together with palmitate and TNF-α. In conclusion, palmitic and TNF-α co-induced MIP-1α in human monocytic cells via TLR4-IRF3 and signaling pathways involving c-Jun / NF-kB. Importantly, oxidative stress leads to ROS-driven amplification MIP-1α, which may have significance for inflammatory metabolism.

MIP-1α Expression Induced by Co-Stimulation of Human Monocytic Cells with Palmitate and TNF-α Involves the TLR4-IRF3 Pathway and Is Amplified by Oxidative Stress
MIP-1α Expression Induced by Co-Stimulation of Human Monocytic Cells with Palmitate and TNF-α Involves the TLR4-IRF3 Pathway and Is Amplified by Oxidative Stress

Progress in Regulating Cancer tumorigenicity and metastasis through TrkB signaling

Clinical Pathology various human malignancies supported by tropomyosin receptor kinase (Trk) B specific receptor TrkB which is derived neurotrophic factor from binding brain (BDNF) and TrkB .TrkB fusion protein has been observed for over-expressed in many cancer patients. In addition, they observed in several cell types. A multiple signaling pathways may be affected by abnormal activation pathway of BDNF / TrkB. These signaling pathways in-clude PI3K / Akt, transactivation of EGFR, phospholipase C-gamma (PLCγ) pathway, Ras-Raf-MEK-ERK pathway, Jak / STAT pathway, and nuclear factor kappa-light-chain-enhancer of B cells activated (NF-kB) pathway.

anti-NFκB-p100/p52 (Ab-869)

LF-PA20318 100 ul
EUR 400.8
Description: Rabbit polyclonal to NFκB-p100/p52

NFκB-p100/p52 (Ab-869) Antibody

E021016-1 50μg/50μl
EUR 100
Description: Available in various conjugation types.

NFκB-p100/p52 (Ab-869) Antibody

E021016-2 100μg/100μl
EUR 170
Description: Available in various conjugation types.

Polyclonal NF-KB p100 Antibody (Ab-869)

APR05373G 0.1ml
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human NF-KB p100 (Ab-869). This antibody is tested and proven to work in the following applications:

NF-κB p100/p52 (Ab-869) Antibody

E11-7165B 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Abt-869

20-abx182361
  • EUR 2163.60
  • EUR 661.20
  • 100 mg
  • 10 mg

CK 869

B5788-10 10 mg
EUR 313.2

CK 869

B5788-25 25 mg
EUR 616.8

CK 869

B5788-5 5 mg
EUR 204

ABT-869

1615-1 each
EUR 255.6

ABT-869

1615-5 each
EUR 738

CK-869

HY-16927 100mg
EUR 1011.6

CK 869

B5788-100 100mg
EUR 1637
Description: actin-related protein 2/3 (Arp2/3) complex inhibitor

CK 869

B5788-50 50mg
EUR 926
Description: actin-related protein 2/3 (Arp2/3) complex inhibitor

Linifanib (ABT-869)

A2949-100 100 mg
EUR 936
Description: Linifanib (ABT-869) is an effective ATP-competitive tyrosine kinase inhibitor against the platelet-derived growth factor (PDGF) receptor and the vascular endothelial growth factor receptor (VEGFR) families, including constitutively active FMS-like receptor tyrosine kinase 3 (FLT3) [1][2].

Linifanib (ABT-869)

A2949-25 25 mg
EUR 393.6
Description: Linifanib (ABT-869) is an effective ATP-competitive tyrosine kinase inhibitor against the platelet-derived growth factor (PDGF) receptor and the vascular endothelial growth factor receptor (VEGFR) families, including constitutively active FMS-like receptor tyrosine kinase 3 (FLT3) [1][2].

Linifanib (ABT-869)

A2949-5 5 mg
EUR 170.4
Description: Linifanib (ABT-869) is an effective ATP-competitive tyrosine kinase inhibitor against the platelet-derived growth factor (PDGF) receptor and the vascular endothelial growth factor receptor (VEGFR) families, including constitutively active FMS-like receptor tyrosine kinase 3 (FLT3) [1][2].

Linifanib (ABT-869)

A2949-5.1 10 mM (in 1mL DMSO)
EUR 234
Description: Linifanib (ABT-869) is an effective ATP-competitive tyrosine kinase inhibitor against the platelet-derived growth factor (PDGF) receptor and the vascular endothelial growth factor receptor (VEGFR) families, including constitutively active FMS-like receptor tyrosine kinase 3 (FLT3) [1][2].

Linifanib (ABT-869)

E1KS1003 5mg
EUR 625.2

HER2/neu (869-877)

5-01300 4 x 5mg Ask for price

HER2 / neu (869-877) Peptide

20-abx266601
  • EUR 477.60
  • EUR 292.80
  • EUR 376.80
  • 10 mg
  • 2 mg
  • 5 mg

Recombinant Clostridium Acetobutylicum mutS Protein (aa 1-869)

VAng-Lsx7711-inquire inquire Ask for price
Description: Clostridium Acetobutylicum DNA mismatch repair protein MutS, recombinant protein.

Recombinant Staphylococcus Aureus clpB Protein (aa 1-869) (strain MW2)

VAng-Cr5673-inquire inquire Ask for price
Description: Staphylococcus Aureus (strain MW2) Chaperone protein ClpB (clpB), recombinant protein.

Recombinant Staphylococcus Aureus clpB Protein (aa 1-869) (strain MRSA252)

VAng-Cr5674-inquire inquire Ask for price
Description: Staphylococcus Aureus (strain MRSA252) Chaperone protein ClpB (clpB), recombinant protein.

Recombinant Staphylococcus Aureus clpB Protein (aa 1-869) (strain N315)

VAng-Cr5675-inquire inquire Ask for price
Description: Staphylococcus Aureus (strain N315) Chaperone protein ClpB (clpB), recombinant protein.

Activin AB

PR15011 5 ug
EUR 577.2

Soyasaponin Ab

HY-N3026 5mg
EUR 338.4

AB-423

HY-112142 100mg
EUR 2469.6

AB-MECA

HY-19365 5mg
EUR 456

AB-680

HY-125286 10mg
EUR 2126.4

Thyroid Ab/ Rat Thyroid Ab ELISA Kit

ELA-E0844r 96 Tests
EUR 1063.2

GNRHR-Ab/ Rat GNRHR- Ab ELISA Kit

ELA-E0962r 96 Tests
EUR 1063.2

MAG Ab/ Rat MAG Ab ELISA Kit

ELA-E0995r 96 Tests
EUR 1063.2

DNP-Ab/ Rat DNP- Ab ELISA Kit

ELA-E1122r 96 Tests
EUR 1063.2

ENA-Ab/ Rat ENA- Ab ELISA Kit

ELA-E1124r 96 Tests
EUR 1063.2

RNP-Ab/ Rat RNP- Ab ELISA Kit

ELA-E1129r 96 Tests
EUR 1063.2

PDGF-AB/ Rat PDGF- AB ELISA Kit

ELA-E0112r 96 Tests
EUR 1063.2

MBP-Ab/ Rat MBP- Ab ELISA Kit

ELA-E0170r 96 Tests
EUR 1063.2

MC Ab/ Rat MC Ab ELISA Kit

ELA-E0390r 96 Tests
EUR 1063.2

TPO-Ab/ Rat TPO- Ab ELISA Kit

ELA-E0442r 96 Tests
EUR 1063.2

Mouse ACV-AB(Activin AB) ELISA Kit

EM0312 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml

Rat Activin AB,ACV-AB ELISA Kit

SL1432Ra - Ask for price

Camel Theileria Ab,Thi-Ab ELISA Kit

SL0060Cm - Ask for price

Camel Brucella Antibody Ab(Brucella-Ab)ELISA Kit

SL0041Cm - Ask for price

Human Brucella Antibody Ab(Brucella-Ab)ELISA Kit

SL3349Hu 96 Tests
EUR 468

Rat TG-ab(anti-Thyroglobulin Ab) ELISA Kit

ELK8353-48T 48T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Rat TG-Ab protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat TG-Ab. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat TG-Ab in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat TG-ab(anti-Thyroglobulin Ab) ELISA Kit

ELK8353-96T 96T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Rat TG-Ab protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat TG-Ab. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat TG-Ab in the samples is then determined by comparing the OD of the samples to the standard curve.

Human TG-ab(anti-Thyroglobulin Ab) ELISA Kit

ELK9250-48T 48T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Human TG-Ab protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TG-Ab. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human TG-Ab in the samples is then determined by comparing the OD of the samples to the standard curve.

Human TG-ab(anti-Thyroglobulin Ab) ELISA Kit

ELK9250-96T 96T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Human TG-Ab protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TG-Ab. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human TG-Ab in the samples is then determined by comparing the OD of the samples to the standard curve.

PDGF AB protein

30R-2610 10 ug
EUR 430.8
Description: Purified recombinant Human PDGF AB protein

PDGF AB protein

30R-AP003 10 ug
EUR 327.6
Description: Purified recombinant Human PDGF AB protein

AB-Pinaca Antibody

abx023942-1mg 1 mg
EUR 744

AB-Pinaca Antibody

abx023943-1mg 1 mg
EUR 744

NGAL (Capture Ab)

20-abx019240
  • EUR 176.40
  • EUR 777.60
  • EUR 260.40
  • EUR 493.20
  • EUR 126.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50 ug

NGAL (Capture Ab)

20-abx019241
  • EUR 176.40
  • EUR 777.60
  • EUR 493.20
  • 100 ug
  • 1 mg
  • 500 ug

NGAL (Detection Ab)

abx019242-100ug 100 ug
EUR 777.6

Apoa5 (ab) Antibody

BF0615 200ul
EUR 540

rHu PDGF-AB

AK8282-0002 2µg Ask for price

rHu PDGF-AB

AK8282-0010 10µg Ask for price

rHu PDGF-AB

AK8282-0100 100µg Ask for price

rHu PDGF-AB

AK8282-1000 1mg Ask for price

Elk-1 Ab

3387-100 each
EUR 405.6

AB-2950 MPEC

351201 5unit
EUR 334.8
Description: Super oxide(O2) reaction system L ight Emittingreagent

AB-2960 BactoLumix

3512020 2unit
EUR 378
Description: Menadione oxidation-reduction reaction system for probiotic measurement

AB-3000B Cellgraph

3600000 unit
EUR 120

Ab buffer kit

28903059 EACH
EUR 184.8

Apoa5 (ab) Antibody

abx010415-100ul 100 ul
EUR 493.2

Activin AB, CF

PR15011CF 5 ug
EUR 577.2

PDGF - AB Human

PR27062 2 ug
EUR 229.2

Ab Rabbit GluR2*

P40014-100uL 100uL Ask for price

Ab Rabbit MARCKS*

P40017-100uL 100uL Ask for price

Ab MS GluR1*

P80000-100uL 100uL Ask for price

AB-2950 MPEC

3512010 each
EUR 6600

Human Serum AB

SC00B14 100 ml
EUR 434.4

CD2 Ab Magbeads

E601AB001 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD3 Ab Magbeads

E601AB002 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD4 Ab Magbeads

E601AB003 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD14 Ab Magbeads

E601AB005 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD15 Ab Magbeads

E601AB006 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD19 Ab Magbeads

E601AB007 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD20 Ab Magbeads

E601AB008 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD25 Ab Magbeads

E601AB009 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD34 Ab Magbeads

E601AB010 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD44 Ab Magbeads

E601AB011 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD45 Ab Magbeads

E601AB012 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD63M Ab Magbeads

E601AB014 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

HSP70 Ab Magbeads

E601AB016 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

EPCAM Ab Magbeads

E601AB017 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CEA Ab Magbeads

E602AB004 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

AFP Ab Magbeads

E602AB005 ~2X109 cells, 1ml
EUR 595
Description: Available in various conjugation types.

PSA Ab Magbeads

E602AB006 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

NSE Ab Magbeads

E602AB008 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CK19 Ab Magbeads

E602AB010 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CA199 Ab Magbeads

E602AB012 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CA242 Ab Magbeads

E602AB013 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CA724 Ab Magbeads

E602AB014 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CA125 Ab Magbeads

E602AB015 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

TPA Ab Magbeads

E602AB016 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

SCCA Ab Magbeads

E602AB017 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

Ferritin Ab Magbeads

E602AB018 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CA50 Ab Magbeads

E602AB019 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CK8 Ab Magbeads

E602AB020 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CK18 Ab Magbeads

E602AB021 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CK20 Ab Magbeads

E602AB022 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

HE4 Ab Magbeads

E602AB027 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

GPC1 Ab Magbeads

E602AB030 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

SUPAR Ab Magbeads

E602AB031 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CKMB Ab Magbeads

E603AB001 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CTNI Ab Magbeads

E603AB004 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CRP Ab Magbeads

E603AB006 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

SAV Ab Magbeads

E2790053 100ul
EUR 225
Description: Available in various conjugation types.

SAV Ab Magbeads

E2790054 100ul
EUR 225
Description: Available in various conjugation types.

Apoa5 (ab) Antibody

E10-20006 100μg/100μl
EUR 225
Description: Available in various conjugation types.

H.Pylori Ab test

04FK10 30 tests/kit
EUR 71.5

Chagas Ab test

49FK10 25 tests/kit
EUR 55

ELISA kit for Mouse ACV-AB (Activin AB)  Kit

E-EL-M2660 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Mouse ACV-AB (Activin AB)  Kit in samples from Serum, Plasma, Cell supernatant

n-DNA-Ab/ Rat n- DNA- Ab ELISA Kit

ELA-E1126r 96 Tests
EUR 1063.2

Sc1-70-Ab/ Rat Sc1- 70- Ab ELISA Kit

ELA-E1131r 96 Tests
EUR 1063.2

IFN-Gamma ab/ Rat IFN- Gamma ab ELISA Kit

ELA-E1716r 96 Tests
EUR 1063.2

G-CSF ab/ Rat G- CSF ab ELISA Kit

ELA-E1717r 96 Tests
EUR 1063.2

ACV-AB ELISA Kit| Mouse Activin AB ELISA Kit

EF012990 96 Tests
EUR 826.8

Feline Immunodefiency Virus Ab (FIV Ab) Rapid Test Kit

HG039 10 Tests/Kit
EUR 21
Description: Contents: (1) 10 Tests/Kit   (cassette,disposable dropper,desiccant) (2) 10 Assay buffer tubes (3) 10 Sterile swabs (4) 1 Instruction manual

Human  Anti Amyloid beta Ab (Abeta-Ab)ELISA Kit

SL3770Hu 96 Tests
EUR 468

Human Platelet Derived Growth Factor AB (PDGF-AB) CLIA Kit

abx197488-96tests 96 tests
EUR 990

Rat Platelet-Derived Growth Factor AB (PDGF-AB) CLIA Kit

abx197512-96tests 96 tests
EUR 990

Human Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

201-12-0138 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Pig Platelet-Derived Growth Factor AB (PDGF-AB) ELISA kit

CSB-EQ027978PI-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Pig Platelet-Derived Growth Factor AB (PDGF-AB) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Pig Platelet-Derived Growth Factor AB (PDGF-AB) ELISA kit

1-CSB-EQ027978PI
  • EUR 1080.00
  • EUR 6571.20
  • EUR 3480.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Pig Platelet-Derived Growth Factor AB (PDGF-AB) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

CN-03255H1 96T
EUR 560.4

Human Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

CN-03255H2 48T
EUR 379.2

Rat Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

CN-01590R1 96T
EUR 548.4

Rat Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

CN-01590R2 48T
EUR 367.2

Mouse Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

CN-02423M1 96T
EUR 548.4

Mouse Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

CN-02423M2 48T
EUR 367.2

Human Platelet-Derived Growth Factor AB, PDGF-AB ELISA kit

CSB-E04701h-24T 1 plate of 24 wells
EUR 198
Description: Quantitative sandwich ELISA kit for measuring Human Platelet-Derived Growth Factor AB, PDGF-AB in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Platelet-Derived Growth Factor AB, PDGF-AB ELISA kit

1-CSB-E04701h
  • EUR 867.60
  • EUR 5859.60
  • EUR 3109.20
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitative sandwich ELISA kit for measuring Human Platelet-Derived Growth Factor AB, PDGF-AB in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Platelet-Derived Growth Factor AB, PDGF-AB ELISA kit

CSB-E04703r-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Rat Platelet-Derived Growth Factor AB, PDGF-AB in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Platelet-Derived Growth Factor AB, PDGF-AB ELISA kit

1-CSB-E04703r
  • EUR 843.60
  • EUR 5811.60
  • EUR 3084.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat Platelet-Derived Growth Factor AB, PDGF-AB in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rabbit Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit

CSB-E15910Rb-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Rabbit Platelet-Derived Growth Factor AB (PDGF-AB) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rabbit Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit

1-CSB-E15910Rb
  • EUR 843.60
  • EUR 5811.60
  • EUR 3084.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rabbit Platelet-Derived Growth Factor AB(PDGF-AB) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat PDGF-AB(Platelet-Derived Growth Factor AB) ELISA Kit

ER0056 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 4.688pg/ml

Rabbit PDGF-AB(Platelet Derived Growth Factor AB) ELISA Kit

ERB0095 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rabbit;Sensitivity: 0.938 ng/ml

Rat Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit

GA-E0700RT-48T 48T
EUR 447.6

Rat Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit

GA-E0700RT-96T 96T
EUR 730.8

Human Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit

GA-E0076HM-48T 48T
EUR 346.8

Human Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit

GA-E0076HM-96T 96T
EUR 559.2

Mouse Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit

GA-E0148MS-48T 48T
EUR 403.2

Mouse Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit

GA-E0148MS-96T 96T
EUR 640.8

Human PDGF-AB(Platelet-Derived Growth Factor AB) ELISA Kit

EH0139 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Rat Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit

QY-E10952 96T
EUR 433.2

Mouse Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit

QY-E21208 96T
EUR 433.2

Human Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit

QY-E00586 96T
EUR 480

Human Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

YLA2092HU-48T 48T
EUR 435

Human Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

YLA2092HU-96T 96T
EUR 562.5

Human Platelet-Derived Growth Factor AB (PDGF-AB) ELISA Kit

KTE61272-96T5 96 T×5
EUR 3339
Description: This Human Platelet-Derived Growth Factor AB (PDGF-AB) ELISA Kit employs a two-site sandwich ELISA to quantitate PDGF-AB.

Human Platelet-Derived Growth Factor AB (PDGF-AB) ELISA Kit

KTE61272-96T50 96 T×50
EUR 29639
Description: This Human Platelet-Derived Growth Factor AB (PDGF-AB) ELISA Kit employs a two-site sandwich ELISA to quantitate PDGF-AB.

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The BDNF / TrkB pathway, when over expressed in tumors, correlate with reduced clinical prognosis and short life span of the patient. Targeting the BDNF / TrkB pathway and the use of Trk inhibitors, such as entrectinib, larotrectinib., A promising method for tumor targeted therapy. This review provides an overview of the role of TrkB pathway in the pathogenesis of cancer and its value as a potential therapeutic target.

Tony

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