MIP-1α Expression Induced by Co-Stimulation of Human Monocytic Cells with Palmitate and TNF-α Involves the TLR4-IRF3 Pathway and Is Amplified by Oxidative Stress

MIP-1α Expression Induced by Co-Stimulation of Human Monocytic Cells with Palmitate and TNF-α Involves the TLR4-IRF3 Pathway and Is Amplified by Oxidative Stress

Metabolic inflammation is associated with increased expression of a saturated free fatty acid, proinflammatory cytokines, chemokines, and adipose oxidative stress. Macrophage inflammatory protein (MIP) -1α recruit inflammatory cells such as monocytes, macrophages, and neutrophils in adipose tissue; However, the mechanism of promoting the expression of MIP-1α remains unclear.

We hypothesized that the co-induced by palmitate and tumor necrosis factor (TNF) -α in monocytic cells / macrophages can be further enhanced by the presence of reactive oxygen species (ROS) -mediated oxidative stress MIP-1α. To investigate this, THP-1 cells monocytic and human macrophages primary co-stimulated by palmitate and TNF-α and mRNA and protein levels of MIP-1α was measured by using transcription quantitative reverse, polymerase chain reaction (qRT-PCR) and commercial tests enzyme -linked immunosorbent assay (ELISA), respectively.

Cognate receptors of palmitic, pulses like receptor (TLR) -4, was blunted by genetic ablation, neutralization, and chemical inhibition. The involvement of TLR4-downstream pathway, interferon regulatory factor (IRF) -3 or myeloid differentiation (MYD) -88 factors, determined by using IRF3-siRNA or MyD88-deficient cells. induced oxidative stress in cells by hydrogen peroxide (H2O2) and ROS induction treatment was measured with dichloro-dihydro-fluorescein diacetate (DCFH-DA) assay. Data show that MIP-1α gene expression / protein upregulated in cells co-stimulated by palmitate / TNF-α compared with those stimulated with either palmitic or TNF-α (P <0.05).

Furthermore, TLR4-IRF3 the pathway involved in cooperative induction of MIP-1α in THP-1 cells, and this kooperatititas between palmitate and TNF-α is a clathrin-dependent and is also required signal through the c-Jun and nuclear factor kappa-light- to medium-chain enhancer activated B cells (NF-kB). In particular, the ROS itself induced MIP-1α and could further promote the secretion of MIP-1α together with palmitate and TNF-α. In conclusion, palmitic and TNF-α co-induced MIP-1α in human monocytic cells via TLR4-IRF3 and signaling pathways involving c-Jun / NF-kB. Importantly, oxidative stress leads to ROS-driven amplification MIP-1α, which may have significance for inflammatory metabolism.

MIP-1α Expression Induced by Co-Stimulation of Human Monocytic Cells with Palmitate and TNF-α Involves the TLR4-IRF3 Pathway and Is Amplified by Oxidative Stress
MIP-1α Expression Induced by Co-Stimulation of Human Monocytic Cells with Palmitate and TNF-α Involves the TLR4-IRF3 Pathway and Is Amplified by Oxidative Stress

Progress in Regulating Cancer tumorigenicity and metastasis through TrkB signaling

Clinical Pathology various human malignancies supported by tropomyosin receptor kinase (Trk) B specific receptor TrkB which is derived neurotrophic factor from binding brain (BDNF) and TrkB .TrkB fusion protein has been observed for over-expressed in many cancer patients. In addition, they observed in several cell types. A multiple signaling pathways may be affected by abnormal activation pathway of BDNF / TrkB. These signaling pathways in-clude PI3K / Akt, transactivation of EGFR, phospholipase C-gamma (PLCγ) pathway, Ras-Raf-MEK-ERK pathway, Jak / STAT pathway, and nuclear factor kappa-light-chain-enhancer of B cells activated (NF-kB) pathway.

ABT-869

1615-5
EUR 738

Abt-869

20-abx182361
  • EUR 2163.60
  • EUR 661.20
  • 100 mg
  • 10 mg

CK 869

B5788-10 10 mg
EUR 313.2

CK 869

B5788-25 25 mg
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CK 869

B5788-5 5 mg
EUR 204

CK-869

HY-16927 100mg
EUR 1011.6

Linifanib (ABT-869)

E1KS1003 5mg
EUR 625.2

Linifanib (ABT-869)

A2949-100 100 mg
EUR 936
Description: Linifanib (ABT-869) is an effective ATP-competitive tyrosine kinase inhibitor against the platelet-derived growth factor (PDGF) receptor and the vascular endothelial growth factor receptor (VEGFR) families, including constitutively active FMS-like receptor tyrosine kinase 3 (FLT3) [1][2].

Linifanib (ABT-869)

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EUR 393.6
Description: Linifanib (ABT-869) is an effective ATP-competitive tyrosine kinase inhibitor against the platelet-derived growth factor (PDGF) receptor and the vascular endothelial growth factor receptor (VEGFR) families, including constitutively active FMS-like receptor tyrosine kinase 3 (FLT3) [1][2].

Linifanib (ABT-869)

A2949-5 5 mg
EUR 170.4
Description: Linifanib (ABT-869) is an effective ATP-competitive tyrosine kinase inhibitor against the platelet-derived growth factor (PDGF) receptor and the vascular endothelial growth factor receptor (VEGFR) families, including constitutively active FMS-like receptor tyrosine kinase 3 (FLT3) [1][2].

Linifanib (ABT-869)

A2949-5.1 10 mM (in 1mL DMSO)
EUR 234
Description: Linifanib (ABT-869) is an effective ATP-competitive tyrosine kinase inhibitor against the platelet-derived growth factor (PDGF) receptor and the vascular endothelial growth factor receptor (VEGFR) families, including constitutively active FMS-like receptor tyrosine kinase 3 (FLT3) [1][2].

HER2/neu (869-877)

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HER2 / neu (869-877) Peptide

20-abx266601
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  • EUR 376.80
  • 10 mg
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Protein disulfide-isomerase A3 Recombinant Protein

91-869 0.05 mg
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Description: PDIA3 protein is also known as Protein disulfide-isomerase A3. It is a protein that in humans is encoded by the PDIA3 gene.PDIA3 is an enzyme that belongs to the endoplasmic reticulum and interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. PDIA3 interacts with thiazide-sensitive sodium-chloride cotransporter in the kidney and is induced by glucose deprivation. PDIA3 is part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is important for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.

FABP8 Recombinant Protein

96-869 0.1 mg
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Description: Myelin P2 protein (PMP2) is also known as peripheral myelin protein 2, which is a cytosolic protein found primarily in peripheral nerves. PMP2 is a small, basic, and cytoplasmic lipid binding protein of peripheral myelin. Also, PMP2 may play a role in lipid transport protein in Schwann cells. Furthermore, PMP2 may bind cholesterol.

OxiSelect Human Oxidized HDL ELISA Kit (MDA-HDL Quantitation)

STA-869 96 assays
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Recombinant (E.Coli, His-tag) Human Pancreatitis-Associated Protein-1

RP-869 10 ug
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1-Chlorohexane

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Recombinant Clostridium Acetobutylicum mutS Protein (aa 1-869)

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96 WELL WHITE LOW PROFILE PCR MICROPLATE FOR AB

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Recombinant Staphylococcus Aureus clpB Protein (aa 1-869) (strain MW2)

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Anti-CD4 (Keliximab)-MC-Vc-PAB-MMAE ADC

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Description: This ADC product is comprised of an anti-CD4 monoclonal antibody conjugated via a MC-Vc linker to MMAE

Soyasaponin Ab

HY-N3026 5mg
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HY-112142 100mg
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HY-125286 10mg
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HY-19365 5mg
EUR 456

Activin AB

PR15011 5 ug
EUR 577.2

Mouse ACV-AB(Activin AB) ELISA Kit

EM0312 96T
EUR 628.92
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PDGF-AB/ Rat PDGF- AB ELISA Kit

ELA-E0112r 96 Tests
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AK8282-0002 2µg Ask for price

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30R-2610 10 ug
EUR 430.8
Description: Purified recombinant Human PDGF AB protein

Elk-1 Ab

3387-100
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AB-2950 MPEC

351201 5unit
EUR 334.8
Description: Super oxide(O2) reaction system L ight Emittingreagent

AB-2960 BactoLumix

3512020 2unit
EUR 378
Description: Menadione oxidation-reduction reaction system for probiotic measurement

AB-3000B Cellgraph

3600000 unit
EUR 120

PDGF AB protein

30R-AP003 10 ug
EUR 327.6
Description: Purified recombinant Human PDGF AB protein

NGAL (Capture Ab)

20-abx019240
  • EUR 176.40
  • EUR 777.60
  • EUR 260.40
  • EUR 493.20
  • EUR 126.00
  • 100 ug
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20-abx019241
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  • EUR 777.60
  • EUR 493.20
  • 100 ug
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abx019242-100ug 100 ug
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Apoa5 (ab) Antibody

abx010415-100ul 100 ul
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abx023942-1mg 1 mg
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abx023943-1mg 1 mg
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BF0615 200ul
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Ab Rabbit GluR2*

P40014-100uL 100uL Ask for price

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P40017-100uL 100uL Ask for price

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P80000-100uL 100uL Ask for price

Activin AB, CF

PR15011CF 5 ug
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PDGF - AB Human

PR27062 2 ug
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Human Serum AB

SC00B14 100 ml
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Ab buffer kit

28903059 EACH
EUR 159.6

ELISA kit for Mouse ACV-AB (Activin AB)  Kit

E-EL-M2660 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Mouse ACV-AB (Activin AB)  Kit in samples from Serum, Plasma, Cell supernatant

ACV-AB ELISA Kit| Mouse Activin AB ELISA Kit

EF012990 96 Tests
EUR 826.8

IFN-Gamma ab/ Rat IFN- Gamma ab ELISA Kit

ELA-E1716r 96 Tests
EUR 1063.2

G-CSF ab/ Rat G- CSF ab ELISA Kit

ELA-E1717r 96 Tests
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n-DNA-Ab/ Rat n- DNA- Ab ELISA Kit

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Sc1-70-Ab/ Rat Sc1- 70- Ab ELISA Kit

ELA-E1131r 96 Tests
EUR 1063.2

Mouse monoclonal Anti-HA-tag peptide IgG

AB-10110 100 ug
EUR 562.8

Mouse Monoclonal Anti-Human Interleukin-2 IgG

AB-10210 100 ug
EUR 416.4

Rat Monoclonal Anti-Mouse Interleukin-2 receptor IgG

AB-10310 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human Interleukin-2 receptor IgG

AB-10410 100 ug
EUR 416.4

Rat Monoclonal Anti-Mouse Interleukin-2 IgG

AB-10510 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human Interleukin-3 IgG

AB-10610 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human Interleukin-4 IgG

AB-10710 100 ug
EUR 416.4

Rat Monoclonal Anti-Mouse Interleukin-4 IgG

AB-10810 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human Interleukin-6 IgG

AB-10910 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human Interleukin-7 IgG

AB-11010 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human Interleukin-8 IgG

AB-11110 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human Interleukin-10 IgG

AB-11210 100 ug
EUR 416.4

Rat Monoclonal Anti-Mouse Interleukin-10 IgG

AB-11310 100 ug
EUR 416.4

Rat Monoclonal Anti-Mouse Interleukin-12p40 IgG

AB-11410 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human Interleukin-15 IgG

AB-11510 100 ug
EUR 416.4

Hamster Mono Anti-Mouse CTLA-4 (CD152) IgG

AB-11610 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human Eotaxin-1 (CCL11) IgG

AB-12610 100 ug
EUR 416.4

Mouse Monoclonal Anti-Chlamydia LPS IgG

AB-13010 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human CD8-FITC IgG

AB-13110 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human CD4-FITC IgG

AB-13210 100 ug
EUR 416.4

Rat Monoclonal Anti-Mouse CD80 IgG

AB-13310 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human CD8-biotinylated IgG

AB-13410 100 ug
EUR 416.4

Rat Monoclonal Anti-Mouse CD11a IgG

AB-13510 100 ug
EUR 416.4

Rat Monoclonal Anti-Mouse CD11b-FITC IgG

AB-13610 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human CD3-FITC IgG

AB-13710 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human CD3-biotinylated IgG

AB-13810 100 ug
EUR 416.4

Rat Monoclonal Anti-Mouse B220 (CD45R) IgG

AB-13910 100 ug
EUR 416.4

Rat Monoclonal Anti-Mouse CD90 Thy-1.1 IgG

AB-14010 100 ug
EUR 416.4

Rat Monoclonal Anti-Mouse CD90 Thy-1.2 IgG

AB-14110 100 ug
EUR 416.4

Rat Monoclonal Anti-Mouse CD90 Thy-1 IgG

AB-14210 100 ug
EUR 416.4

Mouse Monoclonal Anti-Dengue Virus Type 2 envelop IgG, aff pure

AB-14310 100 ug
EUR 416.4

Mouse monoclonal Anti-Human CD3 IgG, unlabled

AB-14410 100 ug
EUR 562.8

Mouse Monoclonal Anti-Human CD4 IgG

AB-14510 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human CD8 IgG

AB-14810 100 ug
EUR 416.4

Mouse Monoclonal Anti-Hepatitis B Virus (HBsAg;AD & AY Antigens) IgG

AB-15010 100 ug
EUR 416.4

Mouse Monoclonal Anti-HIV-1 gp120 (PND, principal neutralizing domain) IgG

AB-15110 100 ug
EUR 416.4

Mouse Monoclonal Anti- HIV-1 p24 IgG

AB-15210 100 ug
EUR 416.4

Mouse Monoclonal Anti-HIV-2 gp39 IgG

AB-15310 100 ug
EUR 416.4

Mouse Monoclonal Anti-Hepatitis C Virus (HCV) NS3 IgG

AB-15610 20 ug
EUR 489.6

Mouse Monoclonal Anti-SARS Spike Protein IgG

AB-15710 20 ug
EUR 489.6

Mouse Monoclonal Anti-HIV-1 gp41 IgG

AB-15910 100 ug
EUR 416.4

Rabbit Anti-HIV-1 gp41 IgG

AB-16010 1 ml
EUR 416.4

Mouse Monoclonal Anti-HIV-2 gp39 IgG

AB-16110 1 ml
EUR 416.4

Mouse monoclonal Anti-HIV-2 p17 IgG

AB-16120 100 ug
EUR 562.8

Goat Anti-HIV Virus/Virion IgG (poly)

AB-16130 100 ul
EUR 534

Goat Anti-HIV p24 IgG (poly)

AB-16140 100 ul
EUR 534

Goat Anti-HIV gp120 IgG (poly) IgG

AB-16150 100 ul
EUR 534

Goat Anti-HIV gp41 IgG (poly) IgG

AB-16160 100 ul
EUR 534

Mouse Monoclonal Anti-Hepatitis B Surface Antigen A (HBsAg) IgG

AB-16310 1 ml
EUR 416.4

Rat Monoclonal Anti-Mouse CD4 IgG

AB-16510 100 ug
EUR 416.4

Rat Monoclonal Anti-Mouse IFN-gamma IgG

AB-16610 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human CD4-biotinylated IgG

AB-16710 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human CD5 IgG

AB-17110 100 ug
EUR 416.4

Rat Monoclonal Anti-Mouse CD3 IgG

AB-17510 100 ug
EUR 416.4

Mouse Monoclonal Anti-SARS Nucleocapsid protein IgG

AB-17810 50 ug
EUR 562.8

Mouse Monoclonal Anti-SARS Spike IgG

AB-17910 50 ug
EUR 562.8

Mouse Monoclonal Anti-SARS Nucleocapsid Protein IgG

AB-18010 50 ug
EUR 562.8

Mouse Monoclonal Anti-Myelin Oligodendrocyte Glycoprotein IgG

AB-19910 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human FAS (CD95) Blocking antibody IgG

AB-20410 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human FAS (CD95) Activating antibody IgG

AB-20510 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human CD1A (T6, LEU6) IgG

AB-20610 100 ug
EUR 416.4

Mouse Monoclonal Anti-Human CD2 (T11, LFA-2) IgG

AB-20710 100 ug
EUR 416.4

Rat Monoclonal Anti-Mouse Interleukin-12p75 IgG

AB-20910 100 ug
EUR 416.4

Rabbit Anti HIV-1 gp120

AB-21010 50 ul
EUR 489.6

Mouse Monoclonal Anti-Human c-Myc IgG

AB-21110 100 ug
EUR 416.4

Monoclonal Anti-Dengue Virus Type 1-4 (pan, E antigen) IgG, culture medium

AB-21121 0.5 ml
EUR 634.8

Monoclonal Anti-Dengue Virus Type 2, NS1 IgG

AB-21123 100 ul
EUR 534

Monoclonal Anti-Human Thiopurine S-methyltransferase (TPMT) protein IgG

AB-22123 5 ug
EUR 196.8

Rabbit Anti-Human Interleukin 6 receptor (IL-6RCD126, gp80/IL-6RA)

AB-22124 50 ul
EUR 562.8

Goat Anti-lethal factor (B Anthracis) IgG-biotinylated

LF16-AB 50 ug
EUR 489.6

Goat Anti-Anthrax Edema Factor (B Anthracis) IgG-Biotinylated

EF11-AB 50 ug
EUR 489.6

Analyte Mix

8141-AB 1ML
EUR 182.4

ABgene Strips 8 Tubes

AB-0264 PK250
EUR 161.88

Strips 8 Domed Caps

AB-0265 PK250
EUR 69.54

Strips 8 Tubes+Domed Caps

AB-0266 PK250
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Adhesive PCR Film

AB-0558 PK100
EUR 173.28

1.2ml Storage Plate (ind wrp)

AB-0564 PK50
EUR 255.36

Sealing Mat (Round Cap Pierceable)

AB-0566 PK50
EUR 224.58

GeneFrame - 65 ul (15 x 16 mm)

AB-0577 PK100
EUR 241.68

Adhesive Plate Seal

AB-0580 PK100
EUR 63.84

96-well PCR Plate Non-Skirted natural

AB-0600 PK25
EUR 160.74

96-well PCR Plate Non-Skirted (White)

AB-0600W PK25
EUR 191.52

Strips of 8 Domed Caps (Natural)

AB-0602 PK300
EUR 171

0.2 mL Flat Cap Tubes Natural

AB-0620 PK1000
EUR 102.6

0.2 ml Flat Cap Tubes (Blue)

AB-0620B PK1000
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AB-0620P PK1000
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AB-0620Y PK1000
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Adhesive PCR Foil

AB-0626 PK100
EUR 190.38

Thermo-Fast 48 PCR Plate

AB-0648 PK50
EUR 307.8

96-well Low Profile PCR Plate Non-Skirted

AB-0700 PK25
EUR 171

Gas Permeable Adhesive Seal

AB-0718 PK50
EUR 151.62

Strips 8 L Prfl Tubes+Flat Caps

AB-0773 PK120
EUR 360.24

ABgene Strips of 8 Flat Caps 10x12

AB-0783 PK120
EUR 66.12

Strips 8 Flat Caps

AB-0786 PK300
EUR 144.78

Strips 12 Domed Caps

AB-0853 PK200
EUR 110.58

0.8 ml Storage Plate (1 bag 50 plates)

AB-0859 PK50
EUR 274.74

ABgene Ultra Clear Cap Strips

AB-0866 PK120
EUR 84.36

96-well PCR Plate (Segmented Semi-Skirted)

AB-0900 PK25
EUR 159.6

96-well PCR Plate Semi-Skirted with Raised Deck

AB-1100 PK25
EUR 163.02

ABsolute QPCR Adhesive Seal

AB-1170 PK50
EUR 254.22

Strips of 8 Tubes and Flat Caps

AB-1182 PK250
EUR 232.56

Strips of 8 Tubes & Ultra Clear Cap Strips 10x12

AB-1183 PK120
EUR 397.86

Adhesive Seal Applicator

AB-1391 EACH
EUR 10.26

SuperPlate 96-well PCR Plate Semi-Skirted

AB-2400 PK25
EUR 207.48

SuperPlate 96-well (Skirted L Prfl)

AB-2800 PK25
EUR 278.16

Rat Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

CN-01590R1 96T
EUR 548.4

Rat Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

CN-01590R2 48T
EUR 367.2

Human Platelet-Derived Growth Factor AB, PDGF-AB ELISA kit

CSB-E04701h-24T 1 plate of 24 wells
EUR 198
Description: Quantitative sandwich ELISA kit for measuring Human Platelet-Derived Growth Factor AB, PDGF-AB in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Platelet-Derived Growth Factor AB, PDGF-AB ELISA kit

1-CSB-E04701h
  • EUR 867.60
  • EUR 5859.60
  • EUR 3109.20
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitative sandwich ELISA kit for measuring Human Platelet-Derived Growth Factor AB, PDGF-AB in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Platelet-Derived Growth Factor AB, PDGF-AB ELISA kit

CSB-E04703r-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Rat Platelet-Derived Growth Factor AB, PDGF-AB in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Platelet-Derived Growth Factor AB, PDGF-AB ELISA kit

1-CSB-E04703r
  • EUR 843.60
  • EUR 5811.60
  • EUR 3084.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat Platelet-Derived Growth Factor AB, PDGF-AB in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rabbit Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit

CSB-E15910Rb-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Rabbit Platelet-Derived Growth Factor AB (PDGF-AB) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rabbit Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit

1-CSB-E15910Rb
  • EUR 843.60
  • EUR 5811.60
  • EUR 3084.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rabbit Platelet-Derived Growth Factor AB(PDGF-AB) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Pig Platelet-Derived Growth Factor AB (PDGF-AB) ELISA kit

CSB-EQ027978PI-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Pig Platelet-Derived Growth Factor AB (PDGF-AB) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Pig Platelet-Derived Growth Factor AB (PDGF-AB) ELISA kit

1-CSB-EQ027978PI
  • EUR 1080.00
  • EUR 6571.20
  • EUR 3480.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Pig Platelet-Derived Growth Factor AB (PDGF-AB) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

CN-03255H1 96T
EUR 560.4

Human Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

CN-03255H2 48T
EUR 379.2

Mouse Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

CN-02423M1 96T
EUR 548.4

Mouse Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

CN-02423M2 48T
EUR 367.2

Mouse Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit

GA-E0148MS-48T 48T
EUR 403.2

The BDNF / TrkB pathway, when over expressed in tumors, correlate with reduced clinical prognosis and short life span of the patient. Targeting the BDNF / TrkB pathway and the use of Trk inhibitors, such as entrectinib, larotrectinib., A promising method for tumor targeted therapy. This review provides an overview of the role of TrkB pathway in the pathogenesis of cancer and its value as a potential therapeutic target.

Tony

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