Glyoxal and Methylglyoxal as E-cigarette Vapor Ingredients-Induced Pro-Inflammatory Cytokine and Mucins Expression in Human Nasal Epithelial Cells

Glyoxal and Methylglyoxal as E-cigarette Vapor Ingredients-Induced Pro-Inflammatory Cytokine and Mucins Expression in Human Nasal Epithelial Cells

Background: Glyoxal (GO) and methylglyoxal (MGO) is among the majority of the toxic compounds emitted by electronic cigarettes (e-cigarettes) and cigarette smoke tobacco regularly. respiratory diseases presented mucus over production as their main pathophysiologic features. However, the effects of GO and MGO in pro-inflammatory cytokines and mucin expression in human nasal epithelial cells, as well as the underlying signaling pathway, has not been studied.


Objective: This study was to determine whether the GO and MGO induce pro-inflammatory cytokines, and expression of MUC5AC / 5B via MAPK (MAPK) and nuclear factor-kappa-light-chain-enhancer activated B cells (NF kB) signaling pathway.


Methods: The effect of GO and MGO in pro-inflammatory cytokines, mucins expression and signaling pathways of GO and MGO were investigated using enzyme immunoassay water-soluble tetrazolium salt-1, and immunoblot analysis with specific inhibitors and small interfering RNA.


Results: GO and MGO did not affect cell viability up to 2 mM in human nasal epithelial cells. GO and MGO increased production of pro-inflammatory such as interleukin (IL) -1β and IL-6) and MUC5AC / 5B. In addition, GO and MGO was significantly activated extracellular signal-regulated kinase 1/2 (ERK1 / 2), p38 MAPK and NF-kB. Do ERK1 / 2, p38 MAPK and NF-kB signaling pathway involved in the GO and MGO-induced production of pro-inflammatory cytokines (IL-1β and IL-6) and MUC5AC / 5B, we used specific inhibitors and siRNA transfection. This is significantly suppressed Go and MGO-induced expression of pro-inflammatory cytokines (IL-1β and IL-6) and MUC5AC / 5B.

Conclusions: GO and MGO-induced pro-inflammatory cytokines and expression of MUC5AC / 5B through ERK1 / 2, p38 MAPK and NF-kB in human nasal epithelial cells. These results indicate that GO and MGO may be involved in airway diseases related to hypersecretion of mucus.

Glyoxal and Methylglyoxal as E-cigarette Vapor Ingredients-Induced Pro-Inflammatory Cytokine and Mucins Expression in Human Nasal Epithelial Cells
Glyoxal and Methylglyoxal as E-cigarette Vapor Ingredients-Induced Pro-Inflammatory Cytokine and Mucins Expression in Human Nasal Epithelial Cells

Acyclic Triterpenoid Isolated from Alpinia katsumadai Relieves Chronic Formalin-Induced Rat Paw Inflammation by Inhibiting the phosphorylation of ERK and NF-kB

Chronic and excessive inflammation can damage organs and cause a host of inflammatory diseases such as inflammatory bowel disease, asthma, and rheumatoid arthritis. In this study, we investigated the anti-inflammatory effects of Alpinia katsumadai derived seed-pentahydroxy 2,3,5,22,23-2,6,10,15,19,23-hexamethyl-tetracosa-6,10,14, 18-tetraene (IPM) using lipopolysaccharide (LPS) -stimulated J774 cells and chronic foot rat model of formalin-induced inflammation. In vitro results showed that PHT showed no cytotoxicity and decreased LPS-induced NO secretion.

In addition, PHT inhibit LPS-induced inducible NO synthase (iNOS) and cyclooxygenase 2 expression (COX2) protein. Quantitative real-time PCR results showed that PHT downregulated gene expression of proinflammatory cytokine interleukin-1β (IL-1β) and interleukin-6 (IL-6) but not tumor necrosis factor α (TNF-α). IPM inhibit LPS-induced phosphorylation of extracellular signal-regulated kinase (ERK) and nuclear factor of kappa light chain enhancer activated B cells (NF-kB). In the mouse model, oral administration of 50 mg / kg PHT significantly reduced both the thickness and volume of mouse feet.

These results indicate that IPM has potential anti-inflammatory effects and should be considered as a possible functional material.Human podocytes (HPC) plays an important role in the pathogenesis of kidney disease. In this context, angiotensin II (Ang II) and nuclear factor kappa-light-chain-enhancer activated B cells (NF) plays an important role in Podosit injury.

NFkB p65 (Phospho-Ser281) Antibody

20-abx012581
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Phospho-MLK3 (Thr277+Ser281) Antibody

AF8079 200ul
EUR 376
Description: MLK3 (Phospho-Thr277+Ser281) Antibody detects endogenous levels of MLK3 only when phosphorylated at Thr277+Ser281.

MLK3 (Phospho- Thr277+ Ser281) Antibody

ABF8079 100 ug
EUR 438

NF- kappaB p65 (Phospho-Ser281) Antibody

12000-100ul 100ul
EUR 252

NF- kappaB p65 (Phospho-Ser281) Antibody

12000-50ul 50ul
EUR 187

Phospho- NF- kappaB p65 (Ser281) Antibody

ABF3393 100 ug
EUR 438

Phospho-MLK3 (Thr277+Ser281) Blocking Peptide

AF8079-BP 1mg
EUR 195

Phospho-NF kappaB p65 (Ser281) Antibody

AF3393 200ul
EUR 304
Description: Phospho-NF- kappaB p65 (Ser281) Antibody detects endogenous levels of NF- kappaB p65 only when phosphorylated at Serine 281.

NF?B-p65 (phospho Ser281) Polyclonal Antibody

ES7025-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against NF?B-p65 (phospho Ser281) from Human/Mouse/Rat. This antibody is tested and validated for IHC, WB, ELISA

NF?B-p65 (phospho Ser281) Polyclonal Antibody

ES7025-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against NF?B-p65 (phospho Ser281) from Human/Mouse/Rat. This antibody is tested and validated for IHC, WB, ELISA

NF?B-p65 (phospho Ser281) Polyclonal Antibody

ABP56026-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of NF?B-p65 phospho Ser281) from Human, Mouse, Rat. This NF?B-p65 phospho Ser281) antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human NF?B-p65 around the phosphorylation site of S281

NF?B-p65 (phospho Ser281) Polyclonal Antibody

ABP56026-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of NF?B-p65 phospho Ser281) from Human, Mouse, Rat. This NF?B-p65 phospho Ser281) antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human NF?B-p65 around the phosphorylation site of S281

NF?B-p65 (phospho Ser281) Polyclonal Antibody

ABP56026-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of NF?B-p65 phospho Ser281) from Human, Mouse, Rat. This NF?B-p65 phospho Ser281) antibody is for IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human NF?B-p65 around the phosphorylation site of S281

Phospho-NF kappaB p65 (Ser281) Blocking Peptide

AF3393-BP 1mg
EUR 195

NF- kappaB p65 (Phospho-Ser281) Polyclonal Conjugated Antibody

C12000 100ul
EUR 397

NFkB p65 antibody (Ser281)

70R-32610 100 ug
EUR 327
Description: Rabbit polyclonal NFkB p65 antibody (Ser281)

V-Rel Reticuloendotheliosis Viral Oncogene Homolog A Phospho-Ser281 (RELA pS281) Antibody

20-abx326652
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Phospho-

ABF3803 100 ug
EUR 438

Phospho-

ABD2989 100 ug
EUR 438

IRE1 (Phospho-phospho S724) Antibody

13013-100ul 100ul
EUR 252

IRE1 (Phospho-phospho S724) Antibody

13013-50ul 50ul
EUR 187

IRE1 (Phospho-phospho Y628) Antibody

13014-100ul 100ul
EUR 252

IRE1 (Phospho-phospho Y628) Antibody

13014-50ul 50ul
EUR 187

MSK1(Phospho-phospho S376) Antibody

13389-100ul 100ul
EUR 333

MSK1(Phospho-phospho S376) Antibody

13389-50ul 50ul
EUR 239

phospho-Akt1 (Phospho-Ser479) Antibody

12891-100ul 100ul
EUR 252

phospho-Akt1 (Phospho-Ser479) Antibody

12891-50ul 50ul
EUR 187

phospho-Marcks (phospho-Marcks) Antibody

abx236404-100ug 100 ug
EUR 509

phospho-Marcks (phospho-Marcks) Antibody

abx236405-100ug 100 ug
EUR 551

Phospho- RIP3 (phospho S232) Antibody

ABF3805 100 ug
EUR 438

PAK1(Phospho-S144)+PAK2(Phospho-S141)+PAK3(Phospho-S139) Antibody

13363-100ul 100ul
EUR 333

PAK1(Phospho-S144)+PAK2(Phospho-S141)+PAK3(Phospho-S139) Antibody

13363-50ul 50ul
EUR 239

RPA32/RPA2 (Phospho-phospho T21) Antibody

13390-100ul 100ul
EUR 333

RPA32/RPA2 (Phospho-phospho T21) Antibody

13390-50ul 50ul
EUR 239

MSK1(Phospho-phospho S376) Conjugated Antibody

C13389 100ul
EUR 397

Phospho-MeCP2

MO22150 100 ul
EUR 435

Phospho- Catenin-

ABF3266 100 ug
EUR 438

Phospho- NF-

ABF3375 100 ug
EUR 438

Phospho- AMPK

ABF3494 100 ug
EUR 438

Phospho- IKK-

ABF3496 100 ug
EUR 438

Phospho- AMPK

ABF3514 100 ug
EUR 438

Phospho- Catenin

ABF3541 100 ug
EUR 438

Phospho- Catenin

ABF3542 100 ug
EUR 438

Phospho- Catenin

ABF3543 100 ug
EUR 438

Phospho- HSP90

ABF3615 100 ug
EUR 438

Phospho- IKK

ABF3618 100 ug
EUR 438

Phospho- PKC

ABF3700 100 ug
EUR 438

Phospho- PLC

ABF3704 100 ug
EUR 438

Phospho- PTP

ABF3717 100 ug
EUR 438

Phospho-eIF2

EF018210 96 Tests
EUR 689

Phospho- PP1

ABD2990 100 ug
EUR 438

Phospho- PLC-

ABF5852 100 ug
EUR 438

Phospho- PLC-

ABF5853 100 ug
EUR 438

Phospho- IKK

ABF9243 100 ug
EUR 438

PAK1(Phospho-S144)+PAK2(Phospho-S141)+PAK3(Phospho-S139) Conjugated Antibody

C13363 100ul
EUR 397

Anti-Phospho-Thr356 PRAS40 Antibody, Phospho-Specific

P03629 100ul
EUR 398
Description: Rabbit Polyclonal Phospho-Thr356 PRAS40 Antibody, Phospho-Specific. Validated in WB and tested in Drosophila.

Anti-Myosin phospho S19/phospho S20 Antibody

P11637-1 100uL
EUR 455
Description: Rabbit Polyclonal Myosin phospho S19/phospho S20 Antibody. Validated in IP, WB and tested in Human.

Phospho-Mst1(Thr183)/Mst2 (Phospho-Thr180) Antibody

Ab17467-100 100ul
EUR 482

Erk1(Phospho-T202)+Erk2(Phospho-T185) Antibody

13340-100ul 100ul
EUR 333

Erk1(Phospho-T202)+Erk2(Phospho-T185) Antibody

13340-50ul 50ul
EUR 239

Phospho Histone H1 (Phospho Thr3) Polyclonal Antibody

A68359 100 µg
EUR 483.55
Description: kits suitable for this type of research

ZIPK-Phospho 311Ser (ZIPK-Phospho 311Ser) Antibody

abx239644-100ug 100 ug
EUR 509

phospho-Akt1 (Phospho-Ser479) Polyclonal Conjugated Antibody

C12891 100ul
EUR 397

IRE1 (Phospho-phospho S724) Polyclonal Conjugated Antibody

C13013 100ul
EUR 397

IRE1 (Phospho-phospho Y628) Polyclonal Conjugated Antibody

C13014 100ul
EUR 397

RPA32/RPA2 (Phospho-phospho T21) Conjugated Antibody

C13390 100ul
EUR 397

anti-EGFR (Phospho-Tyr1197)/Her2(Phospho-Tyr1248)

LF-PA0082 100 ul
EUR 334
Description: Rabbit polyclonal to EGFR (Phospho-Tyr1197)/Her2(Phospho-Tyr1248)

Histone H1.3 (Phospho-Thr17) +H1.4 (Phospho-Thr17) Antibody

12793-100ul 100ul
EUR 252

Histone H1.3 (Phospho-Thr17) +H1.4 (Phospho-Thr17) Antibody

12793-50ul 50ul
EUR 187

Erk1(Phospho-T202)+Erk2(Phospho-T185) Conjugated Antibody

C13340 100ul
EUR 397

Kemptide (Phospho-Ser5)

HY-P0291 10mg
EUR 1165

phospho-CREB (Ser133)

RA18008 100 ul
EUR 555

phospho-Synapsin (Ser9)

RA18009 100 ul
EUR 555

phospho-TrkA(Tyr490)

RA18018 100 ul
EUR 584

phospho-Kidins220 (ARMS)

RA19020 100 ul
EUR 304

Phospho-Tau (T534)

RA34005 100 ul
EUR 370

phospho-CD244 Antibody

abx430952-200ul 200 ul
EUR 384

Phospho- PKD1/PKC

ABF3443 100 ug
EUR 438

Phospho- C/EBP

ABF3536 100 ug
EUR 438

Phospho- Insulin Receptor

ABF3619 100 ug
EUR 438

Phospho- PDGF Receptor

ABF3696 100 ug
EUR 438

Phospho- PKD/PKC

ABF3701 100 ug
EUR 438

Phospho- Topoisomerase II

ABF3782 100 ug
EUR 438

Phospho IRS antibody

10R-6733 100 ug
EUR 651
Description: Mouse monoclonal Phospho IRS antibody

phospho EGFR antibody

10R-E125a 100 ul
EUR 749
Description: Mouse monoclonal phospho EGFR antibody

phospho MBP antibody

10R-P120a 100 ug
EUR 814
Description: Mouse monoclonal phospho MBP antibody

Phospho STAT3 antibody

20R-2918 100 ul
EUR 393
Description: Rabbit polyclonal Phospho STAT3 antibody

Phospho Akt antibody

20R-1507 100 ug
EUR 705
Description: Rabbit polyclonal Phospho Akt antibody

Phospho Catenin antibody

20R-1543 100 ug
EUR 705
Description: Rabbit polyclonal Phospho beta Catenin antibody

Phospho-Akt antibody

70R-11723 100 ug
EUR 525
Description: Rabbit polyclonal Phospho-Akt antibody

Phospho-Bad antibody

70R-11732 100 ug
EUR 503
Description: Rabbit polyclonal Phospho-Bad antibody

Phospho-AFX antibody

70R-11733 100 ug
EUR 503
Description: Rabbit polyclonal Phospho-AFX antibody

Phospho-ATF2 antibody

70R-11771 100 ug
EUR 503
Description: Rabbit polyclonal Phospho-ATF2 antibody

Phospho-CAMK2A antibody

70R-11789 100 ul
EUR 503
Description: Rabbit polyclonal Phospho-CAMK2A antibody

Phospho-Elk1 antibody

70R-11792 100 ug
EUR 503
Description: Rabbit polyclonal Phospho-Elk1 antibody

Phospho-MK2 antibody

70R-11823 100 ug
EUR 503
Description: Rabbit polyclonal Phospho-MK2 antibody

Phospho-PKC antibody

70R-11836 100 ug
EUR 503
Description: Rabbit polyclonal Phospho-PKC antibody

Phospho-STAT2 antibody

70R-11847 100 ug
EUR 503
Description: Rabbit polyclonal Phospho-STAT2 antibody

Phospho-STAT3 antibody

70R-11852 100 ug
EUR 503
Description: Rabbit polyclonal Phospho-STAT3 antibody

Phospho-STAT5 antibody

70R-11853 100 ug
EUR 503
Description: Rabbit polyclonal Phospho-STAT5 antibody

Phospho-STAT6 antibody

70R-11854 100 ug
EUR 503
Description: Rabbit polyclonal Phospho-STAT6 antibody

Phospho-SEK1 antibody

70R-11855 100 ug
EUR 503
Description: Rabbit polyclonal Phospho-SEK1 antibody

Phospho-GSK3b antibody

70R-11870 100 ug
EUR 525
Description: Rabbit polyclonal Phospho-GSK3b antibody

Phospho-Lck antibody

70R-11875 100 ug
EUR 525
Description: Rabbit polyclonal Phospho-Lck antibody

Phospho-Raf antibody

70R-11879 100 ug
EUR 525
Description: Rabbit polyclonal Phospho-Raf antibody

Phospho-p53 antibody

70R-11881 100 ug
EUR 645
Description: Rabbit polyclonal Phospho-p53 antibody

Phospho-Mek1 antibody

70R-11884 100 ul
EUR 525
Description: Rabbit polyclonal Phospho-Mek1 antibody

Phospho-SAPK antibody

70R-11932 100 ug
EUR 503
Description: Rabbit polyclonal Phospho-SAPK antibody

Phospho-MARCKS antibody

70R-11974 100 ul
EUR 525
Description: Rabbit polyclonal Phospho-MARCKS antibody

Phospho-BRCA1 antibody

70R-11991 100 ug
EUR 503
Description: Rabbit polyclonal Phospho-BRCA1 antibody

Phospho-VASP antibody

70R-12031 100 ug
EUR 503
Description: Rabbit polyclonal Phospho-VASP antibody

Phospho-Tau antibody

70R-12468 100 ul
EUR 503
Description: Rabbit polyclonal Phospho Tau antibody

Phospho-NR2B antibody

70R-12472 100 ul
EUR 581
Description: Rabbit polyclonal Phospho-NR2B antibody

Phospho-ORF50 antibody

70R-13247 100 ul
EUR 457
Description: Affinity purified Rabbit polyclonal Phospho-ORF50 antibody

phospho Kidins220 antibody

70R-KR013 100 ug
EUR 300
Description: Affinity purified Rabbit polyclonal phospho Kidins220 antibody

phospho-Phospholamban antibody

20R-P121a 100 ug
EUR 967
Description: Rabbit polyclonal phospho-Phospholamban antibody

Phospho-Akt Antibody

3257-100
EUR 419

Phospho-Bad Antibody

3269-100
EUR 403

Phospho-CaMKII Antibody

3384-100
EUR 403

Phospho-PKC Antibody

3451-100
EUR 403

Phospho-Stat2 Antibody

3469-100
EUR 403

Phospho-Stat3 Antibody

3474-100
EUR 403

Phospho-Stat5 Antibody

3475-100
EUR 403

Phospho-Stat6 Antibody

3476-100
EUR 403

Phospho-Lck Antibody

3499-100
EUR 425

Phospho-Raf Antibody

3504-100
EUR 425

Phospho-p53 Antibody

3515-100
EUR 523

Phospho-Tau Antibody

3550R-100
EUR 403

Phospho-MARCKS Antibody

3650-100
EUR 425

Phospho-BRCA1 Antibody

3674-100
EUR 403

Phospho-VASP Antibody

3719-100
EUR 403

Polyclonal Bi-Phospho-YES1(Y537)/Phospho-SRC(Y530) Antibody

APR05154G 0.1ml
EUR 484
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Bi-Phospho-YES1(Y537)/Phospho-SRC(Y530) . This antibody is tested and proven to work in the following applications:

Histone H1.3(Phospho-T17)+Histone H1.4(Phospho-T17) Antibody

13339-100ul 100ul
EUR 333

Histone H1.3(Phospho-T17)+Histone H1.4(Phospho-T17) Antibody

13339-50ul 50ul
EUR 239

Erk1(Phospho-pT202/pY204)+Erk2(Phospho-pT185/pY187) Antibody

13377-100ul 100ul
EUR 333

Erk1(Phospho-pT202/pY204)+Erk2(Phospho-pT185/pY187) Antibody

13377-50ul 50ul
EUR 239

Human ZIPK-Phospho 311Ser (ZIPK-Phospho 311Ser) ELISA Kit

abx392188-96tests 96 tests
EUR 911

Phosphatase And Tensin Homolog Phospho-Ser380/Phospho-Thr382/Phospho-Thr383 (PTEN pS380/pT382/pT383) Antibody

20-abx328543
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Phosphatase And Tensin Homolog Phospho-Ser380/Phospho-Thr382/Phospho-Thr383 (PTEN pS380/pT382/pT383) Antibody

abx333199-100ul 100 ul
EUR 467

Histone H1.3 (Phospho-Thr17) +H1.4 (Phospho-Thr17) Polyclonal Conjugated Antibody

C12793 100ul
EUR 397

Histone H1.3(Phospho-T17)+Histone H1.4(Phospho-T17) Conjugated Antibody

C13339 100ul
EUR 397

Erk1(Phospho-pT202/pY204)+Erk2(Phospho-pT185/pY187) Conjugated Antibody

C13377 100ul
EUR 397

Phospho-ELK1 (Ser383) Antibody

CSB-PA962606-
EUR 335
Description: A polyclonal antibody against Phospho-ELK1 (Ser383). Recognizes Phospho-ELK1 (Ser383) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100

Phospho-ELK1 (Ser383) Antibody

CSB-PA962606-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-ELK1 (Ser383). Recognizes Phospho-ELK1 (Ser383) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100

Phospho-MAPT (Ser404) Antibody

CSB-PA963344-
EUR 335
Description: A polyclonal antibody against Phospho-MAPT (Ser404). Recognizes Phospho-MAPT (Ser404) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

Phospho-MAPT (Ser404) Antibody

CSB-PA963344-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-MAPT (Ser404). Recognizes Phospho-MAPT (Ser404) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

Phospho-CCND1 (Ser90) Antibody

CSB-PA963558-
EUR 335
Description: A polyclonal antibody against Phospho-CCND1 (Ser90). Recognizes Phospho-CCND1 (Ser90) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Phospho-CCND1 (Ser90) Antibody

CSB-PA963558-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-CCND1 (Ser90). Recognizes Phospho-CCND1 (Ser90) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Phospho-HSF1 (Ser307) Antibody

CSB-PA966483-
EUR 335
Description: A polyclonal antibody against Phospho-HSF1 (Ser307). Recognizes Phospho-HSF1 (Ser307) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:1000, IF:1:100-1:200

Phospho-HSF1 (Ser307) Antibody

CSB-PA966483-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-HSF1 (Ser307). Recognizes Phospho-HSF1 (Ser307) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:1000, IF:1:100-1:200

Phospho-SYT1 (Ser309) Antibody

CSB-PA967008-
EUR 335
Description: A polyclonal antibody against Phospho-SYT1 (Ser309). Recognizes Phospho-SYT1 (Ser309) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IF;IF:1:100-1:200

Phospho-SYT1 (Ser309) Antibody

CSB-PA967008-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-SYT1 (Ser309). Recognizes Phospho-SYT1 (Ser309) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IF;IF:1:100-1:200

More recently, transmembrane proteins (Tmem) 63C, a member of Tmem-family found to be expressed in the kidney and associated with Podosit function. In this study, we analyzed the expression and regulation of functional Tmem63c impact on cell viability and apoptosis in HPC in the context of activation of Ang II.

Tony

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