Toll-like receptor 4 (TLR4) recognizes exogenous pathogen associated molecular patterns (PAMPs) and endogenous danger associated molecular patterns (muffle) and the initiation of the innate immune response. opioid receptors (μ, δ, and κ) activates the G-protein inhibition and relieve pain. This review summarizes the following types TLR4 / opioid receptor crosstalk pathways: (a) Opioid receptor agonist non-stereoselectively activates TLR4 signaling pathway in central nervous system (CNS), in the absence of lipopolysaccharide (LPS).
Opioids bind to TLR4, in a way consistent with LPS activates TLR4 signaling, which leads to nuclear factor kappa-light-chain-enhancer activated B cells (NF-kB) expression and production of pro-inflammatory cytokine tumor necrosis factor (TNF) -α , interleukin (IL) -1β, and IL-6. (B) Opioid receptor agonists inhibit LPS-induced TLR4 signaling pathway in the peripheral immune cells. Opioids are operating as pro-inflammatory cytokines, resulting in nerve inflammation in the CNS, but they mediate the immunosuppressive effects in the peripheral immune system.
It is clear that the TLR4 / opioid receptor crosstalk pathways vary depending on cell type and stimulus activates. (C) Both TLR4 and opioid receptor pathway activates mitogen-activated protein kinase (MAPK) pathway. This crosstalk is located downstream of TLR4 and opioid receptor signaling pathway. In addition, the classical opioid receptors can also produce pro-inflammatory effects in the CNS through the MAPK signaling and induces neuroinflammation. (D) agonist opioid receptor induces production of high mobility box group 1 (HMGBcellular (neuron-to-glia or glia-to-neuron) interactions.
This review also summarizes the potential effects of TLR4 / opioid receptor pathway crosstalk on analgesia opioids, immune function, and gastrointestinal motility. opioid non-stereoselectively activate the pathway TLR4, and together with the next release of pro-inflammatory cytokines such as IL-1 by glia, TLR4 signifies the initiation of immune middle of the response signal and modify opioid pharmacodynamics.
Toll-Like Receptor 4 (TLR4)/Opioid Receptor Pathway Crosstalk and Impact on Opioid Analgesia, Immune Function, and Gastrointestinal Motility
The. WET neuropathic pain HMGBof to explained the morphine-induced sensitization persistent, positive feedback has been proposed, this involves a morphine-induced reinforced the initial release of IL-1β and release of aggravated subsequent damping, which increases activation of TLR4 and purinergic receptors P2X7R. opioid receptors (μ, δ, and κ) agonists are involved in many aspects of immunosuppression. The intracellular TLR4 / opioi d receptor signaling crosstalk pathway induces the formation of β-Arr estin-2 / TNF receptor-associated factor 6 (TRAF6) complex, which contributes to morphine-induced inhibition of LPS-induced TNF-α secretion in mast cells. A possible molecular mechanism is that TLR4 pathway was initially triggers the formation of β-Arrestin-2 / TRAF6 complex, which is reinforced by the opioid receptor signaling, indicates that β-Arrestin-2 acts as a functional component of TLR4 pathway.
Rabbit purified IgG, F(ab)'2 fragment (2 mg)
AS10-921
Agrisera AB
2 mg
EUR 220
Goat anti-Human IgG F(ab')2 Affinity purified, Unconjugated
AS21-4573
Agrisera AB
2 mg
EUR 206
Goat anti-Human IgG F(ab')2 Affinity purified, Unconjugated
AS21-4574
Agrisera AB
2 mg
EUR 206
CsoS1A/B/C | Major carboxysome shell protein 1A, AB, 1C
AS14-2760
Agrisera AB
50 µg
EUR 302
Rabbit anti-Human IgM (µ chain), F(ab)'2 Fragment
AS16-3370
Agrisera AB
1 mg
EUR 250
Donkey anti-Mouse IgG (H&L), F(ab)'2 Fragment
AS16-3437
Agrisera AB
1,0 mg
EUR 224
Donkey anti-Rabbit IgG (H&L), F(ab)'2 Fragment
AS16-3521
Agrisera AB
1,0 mg
EUR 206
NFKB1 (Ab-893) Antibody
MBS7131881-01mL
MyBiosource
0.1mL
EUR 270
NFKB1 (Ab-893) Antibody
MBS7131881-5x01mL
MyBiosource
5x0.1mL
EUR 1200
GABBR2 (Ab-893) Antibody
E11-8506B
EnoGene
100μg
EUR 225
Description: Available in various conjugation types.
NFKB1 (Ab-893) Antibody
CSB-PA108426-
Cusabio
each
EUR 402
Description: A polyclonal antibody against NFKB1 (Ab-893). Recognizes NFKB1 (Ab-893) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200
NFKB1 (Ab-893) Antibody
CSB-PA108426-100ul
Cusabio
100ul
EUR 379.2
Description: A polyclonal antibody against NFKB1 (Ab-893). Recognizes NFKB1 (Ab-893) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200
GABBR2 (Ab-893) Antibody
MBS851704-01mg
MyBiosource
0.1mg
EUR 305
GABBR2 (Ab-893) Antibody
MBS851704-01mLAF405L
MyBiosource
0.1mL(AF405L)
EUR 465
GABBR2 (Ab-893) Antibody
MBS851704-01mLAF405S
MyBiosource
0.1mL(AF405S)
EUR 465
GABBR2 (Ab-893) Antibody
MBS851704-01mLAF610
MyBiosource
0.1mL(AF610)
EUR 465
GABBR2 (Ab-893) Antibody
MBS851704-01mLAF635
MyBiosource
0.1mL(AF635)
EUR 465
Goat anti-Human IgG Fc, F(ab)'2 fragment, FITC conjugated
AS10-1236
Agrisera AB
0,5 mg
EUR 233
Goat anti-Human IgG Fc, Biotin conjugated, F(ab)'2 fragment
AS10-806
Agrisera AB
0,5 mg
EUR 206
Goat anti-Rabbit IgG (H&L), F(ab)'2 fragment, Unconjugated
AS10-846
Agrisera AB
1 mg
EUR 206
Goat anti-Human IgG Fc, F(ab)'2 Fragment, DyLight® 488 conjugated, min, cross-reactivity to human IgA, IgM or IgG F(ab)'2 fragment
AS16-3353
Agrisera AB
0,5 mg
EUR 196
Donkey anti-Mouse IgG (H&L), F(ab)'2 Fragment, FITC conjugated
AS16-3450
Agrisera AB
0,5 mg
EUR 206
Donkey anti-Mouse IgG (H&L), F(ab)'2 Fragment, HRP conjugated
AS16-3454
Agrisera AB
0,5 mg
EUR 233
Donkey anti-Mouse IgG (H&L), F(ab)'2 Fragment, TRITC conjugated
AS16-3467
Agrisera AB
0,5 mg
EUR 206
Goat anti-Human IgM (µ chain), F(ab)'2 fragment, HRP conjugated
AS10-1009
Agrisera AB
0,5 mg
EUR 246
Goat anti-Rabbit IgG (H&L), F(ab)'2 fragment, FITC conjugated
AS10-1011
Agrisera AB
0,5 mg
EUR 185
Goat anti-Rabbit IgG (H&L), F(ab)'2 fragment, TRITC conjugated
AS10-1018
Agrisera AB
0,5 mg
EUR 185
Goat anti-Human IgG + IgA + IgM, F(ab)'2 fragment, HRP conjugated
AS10-1039
Agrisera AB
0,5 mg
EUR 246
Rabbit anti-Goat IgG (H&L), F(ab)'2 fragment, HRP conjugated
AS10-1045
Agrisera AB
0,5 mg
EUR 246
Goat anti-Human IgA (alpha chain), F(ab)'2 fragment, FITC conjugated
AS10-1076
Agrisera AB
0,5 mg
EUR 239
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, Biotin conjugated
AS10-1081
Agrisera AB
0,5 mg
EUR 233
Goat anti-Human IgA (alpha chain), F(ab)'2 fragment, TRITC conjugated
AS10-1097
Agrisera AB
0,5 mg
EUR 233
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, ALP conjugated
AS10-1139
Agrisera AB
0,5 mg
EUR 233
Goat anti-Human IgM (µ chain), F(ab)'2 fragment, Biotin conjugated
AS10-1200
Agrisera AB
0,5 mg
EUR 246
Goat anti-Human IgA + IgG + IgM, F(ab)'2 fragment, ALP conjugated
AS10-1222
Agrisera AB
0,5 mg
EUR 233
Goat anti-Human IgM (µ chain), F(ab)'2 fragment, ALP conjugated
AS10-1237
Agrisera AB
0,5 mg
EUR 246
Goat anti-Human IgA + IgG + IgM, F(ab)'2 fragment, Biotin conjugated
AS10-1253
Agrisera AB
0,5 mg
EUR 233
Goat anti-Human IgA + IgG + IgM, F(ab)'2 fragment, FITC conjugated
AS10-1275
Agrisera AB
0,5 mg
EUR 233
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, TRITC conjugated
AS10-1289
Agrisera AB
0,5 mg
EUR 175
Goat anti-Human IgG (H&L), F(ab)'2 fragment, FITC conjugated
AS10-1295
Agrisera AB
0,5 mg
EUR 185
Goat anti-Human IgA + IgG + IgM, F(ab)'2 fragment, TRITC conjugated
AS10-1306
Agrisera AB
0,5 mg
EUR 233
Goat anti-Human IgA heavy (alpha chain), F(ab)'2 fragment, Unconjugated
AS10-743
Agrisera AB
1 mg
EUR 206
Goat anti-Human IgG (H&L), F(ab)'2 fragment, ALP conjugated
AS10-774
Agrisera AB
0,5 mg
EUR 206
Goat anti-Human IgG (H&L), F(ab)'2 fragment, Biotin conjugated
AS10-775
Agrisera AB
0,5 mg
EUR 206
Goat anti-Human IgG (H&L), F(ab)'2 fragment, HRP conjugated
AS10-779
Agrisera AB
0,5 mg
EUR 206
Goat anti-Human IgG Fc, F(ab)'2 fragment, Affinity purified, Unconjugated
AS10-805
Agrisera AB
1 mg
EUR 233
Goat anti-Rabbit IgG (H&L), F(ab)'2 fragment, ALP conjugated
AS10-848
Agrisera AB
0,5 mg
EUR 233
Goat anti-Rabbit IgG (H&L), F(ab)'2 fragment, Biotin conjugated
AS10-849
Agrisera AB
0,5 mg
EUR 206
Goat anti-Rabbit IgG (H&L), F(ab)'2 fragment, HRP conjugated
AS10-852
Agrisera AB
0,5 mg
EUR 206
Goat anti-Human IgG (H&L), F(ab)'2 fragment, TRITC conjugated
AS10-946
Agrisera AB
0,5 mg
EUR 185
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, FITC conjugated
AS10-967
Agrisera AB
0,5 mg
EUR 175
Goat anti-Human IgM (µ chain), F(ab)'2 fragment, FITC conjugated
AS10-991
Agrisera AB
0,5 mg
EUR 246
Rabbit anti-Goat IgG (H&L), F(ab)'2 fragment, Biotin conjugated
AS10-997
Agrisera AB
0,5 mg
EUR 246
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, HRP conjugated
AS10-998
Agrisera AB
0,5 mg
EUR 185
Goat anti-Human IgM (µ chain), F(ab)'2 fragment, Affinity purified, Unconjugated
AS10-1029
Agrisera AB
1 mg
EUR 246
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, Affinity purified, Unconjugated
AS10-1163
Agrisera AB
1 mg
EUR 175
Goat anti-Human IgA + IgG + IgM, F(ab)'2 fragment, Affinity purified, Unconjugated
AS10-1184
Agrisera AB
1 mg
EUR 175
TSH (beta) | thyroid stimulating hormone (Affinity purified, F(ab)2' fragment, goat antibody)
AS10-1325
Agrisera AB
0,5 mg
EUR 532
Goat anti-Human IgA heavy (alpha chain), F(ab)'2 fragment, Biotin conjugated
AS10-745
Agrisera AB
0,5 mg
EUR 233
Goat anti-Human IgA heavy (alpha chain), F(ab)'2 fragment, HRP conjugated
AS10-746
Agrisera AB
0,5 mg
EUR 206
Goat anti-Human IgG (H&L), F(ab)'2 fragment, Affinity purified, Unconjugated
AS10-773
Agrisera AB
1 mg
EUR 206
Rabbit anti-Goat IgG (H&L), F(ab)'2 fragment, Affinity purified, Unconjugated
AS10-960
Agrisera AB
1 mg
EUR 233
Donkey anti-Mouse IgG (H&L), F(ab)'2 fragment, DyLight® 633 conjugated
AS12-2182
Agrisera AB
0,5 mg
EUR 206
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, DyLight® 633 conjugated
AS12-2189
Agrisera AB
0,5 mg
EUR 206
Rabbit anti-Goat IgG (H&L), F(ab)'2 fragment, DyLight® 800 conjugated
AS12-2381
Agrisera AB
0,5 mg
EUR 233
Donkey anti-Mouse IgG (H&L), F(ab)'2 fragment, DyLight® 800 conjugated
AS12-2428
Agrisera AB
0,5 mg
EUR 246
Donkey anti-Rabbit IgG (H&L), F(ab)'2 Fragment, DyLight® 488 conjugated
AS16-3526
Agrisera AB
0,5 mg
EUR 233
Goat anti-Rabbit IgG (H&L), F(ab)'2 Fragment, DyLight® 488 conjugated
AS16-3527
Agrisera AB
0,5 mg
EUR 202
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, DyLight® 488 conjugated
AS10-1220
Agrisera AB
0,5 mg
EUR 206
Goat anti-Rat IgG (H&L), F(ab)'2 fragment, HRP conjugated, min,reactivity to human, mouse IgG
AS10-1145
Agrisera AB
0,5 mg
EUR 246
Goat anti-Human IgG Fc, F(ab)'2 fragment, Biotin conjugated, min, cross-reactivity bovine/mouse/rabbit serum
AS10-814
Agrisera AB
0,5 mg
EUR 246
Goat anti-Human IgG Fc, F(ab)'2 fragment, HRP conjugated, min, cross-reactivity bovine/mouse/rabbit serum
AS10-817
Agrisera AB
0,5 mg
EUR 233
NFκB-p105 (Ab-893) Antibody
21018
SAB
100ul
EUR 319
Goat anti-Human IgM (µ chain), F(ab)'2 Fragment, min, cross-reactivity to IgG from human or mouse
AS16-3371
Agrisera AB
1,0 mg
EUR 238
Goat anti-Human IgG Fc, F(ab)'2 fragment, TRITC conjugated, min, cross-reactivity to bovine,mouse,rabbit serum
AS10-1001
Agrisera AB
0,5 mg
EUR 246
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, FITC conjugated, min, cross-reactivity to human IgG/serum
AS10-1002
Agrisera AB
0,5 mg
EUR 233
Goat anti-Rat IgG (H&L), F(ab)'2 fragment, Biotin conjugated, min, cross-reactivity to human, mouse IgG
AS10-1023
Agrisera AB
0,5 mg
EUR 246
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, TRITC conjugated, min, cross-reactivity to human IgG/serum
As10-1071
Agrisera AB
0,5 mg
EUR 233
Goat anti-Rat IgG (H&L), F(ab)'2 fragment, TRITC conjugated, min, cross-reactivity to human, mouse IgG
AS10-1088
Agrisera AB
0,5 mg
EUR 246
Goat anti-Human IgG Fc, F(ab)'2 fragment, FITC conjugated, min, cross-reactivity to bovine,mouse,rabbit serum
AS10-1099
Agrisera AB
0,5 mg
EUR 246
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, HRP conjugated, min, cross-reactivity to human IgG/serum
AS10-1189
Agrisera AB
0,5 mg
EUR 233
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, ALP conjugated, min, cross-reactivity to human IgG/serum
AS10-1193
Agrisera AB
0,5 mg
EUR 246
Goat anti-Rat IgG (H&L), F(ab)'2 fragment, FITC conjugated, min, cross-reactivity to human, mouse IgG
AS10-1234
Agrisera AB
0,5 mg
EUR 246
Goat anti-Human IgG (H&L), F(ab)'2 fragment, Biotin conjugated, min, cross-reactivity bovine/mouse/rabbit serum
AS10-782
Agrisera AB
0,5 mg
EUR 233
Goat anti-Human IgG (H&L), F(ab)'2 fragment, HRP conjugated, min, cross-reactivity bovine/mouse/rabbit serum
AS10-785
Agrisera AB
0,5 mg
EUR 233
Goat anti-Human IgG Fc, F(ab)'2 fragment, ALP conjugated, min, cross-reactivity to bovine/mouse/rabbit serum
AS10-813
Agrisera AB
0,5 mg
EUR 246
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, Biotin conjugated, min, cross-reactivity to human IgG/serum
AS10-981
Agrisera AB
0,5 mg
EUR 233
Goat anti-Human IgG (H&L), F(ab)'2 fragment, FITC conjugated, min, cross-reactivity to bovine,mouse,rabbit serum
AS10-1015
Agrisera AB
0,5 mg
EUR 233
Rabbit anti-Goat IgG (H&L), F(ab)'2 fragment, FITC conjugated, min, cross-reactivity to human, mouse,Rat IgG
AS10-1058
Agrisera AB
0,5 mg
EUR 246
Rabbit anti-Goat IgG (H&L), F(ab)'2 fragment, HRP conjugated, min, cross-reactivity to human, mouse,Rat IgG
AS10-1065
Agrisera AB
0,5 mg
EUR 246
Goat anti-Human IgM (µ chain), F(ab)'2 fragment, TRITC conjugated, min, cross-reactivity to human IgG or IgA
AS10-1090
Agrisera AB
0,5 mg
EUR 233
Goat anti-Human IgG (H&L), F(ab)'2 fragment, TRITC conjugated, min, cross-reactivity to bovine,mouse,rabbit serum
AS10-1157
Agrisera AB
0,5 mg
EUR 233
Goat anti-Rat IgG (H&L), F(ab)'2 fragment, Affinity purified, Unconjugated, min, cross-reactivity to human, mouse IgG
AS10-1215
Agrisera AB
1 mg
EUR 233
Goat anti-Human IgM (µ chain), F(ab)'2 fragment, FITC conjugated, min, cross-reactivity to human IgG or IgA
AS10-1287
Agrisera AB
0,5 mg
EUR 259
Goat anti-Human IgM (µ chain), F(ab)'2 fragment, Affinity purified, Unconjugated, min, cross-reactivity to human IgA+IgG
AS10-1296
Agrisera AB
1 mg
EUR 233
Goat anti-Human IgM (µ chain), F(ab)'2 fragment, ALP conjugated, min, cross-reactivity to human IgG or IgA
AS10-1298
Agrisera AB
0,5 mg
EUR 273
Goat anti-Human IgG (H&L), F(ab)'2 fragment, ALP conjugated, min, cross-reactivity to bovine/mouse/rabbit serum
AS10-781
Agrisera AB
0,5 mg
EUR 206
Goat anti-Human IgG Fc, F(ab)'2 fragment, Affinity purified, Unconjugated, min, cross-reactivity to bovine/mouse/rabbit serum
AS10-812
Agrisera AB
1 mg
EUR 233
Goat anti-Human IgM (µ chain), F(ab)'2 fragment, HRP conjugated, min, cross-reactivity to human IgG or IgA
AS10-959
Agrisera AB
0,5 mg
EUR 246
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, Affinity purified, Unconjugated, min, cross-reactivity to human IgG/serum
AS10-961
Agrisera AB
1 mg
EUR 233
Goat anti-Human IgM (µ chain), F(ab)'2 fragment, Biotin conjugated, min, cross-reactivity to human IgG or IgA
AS10-979
Agrisera AB
0,5 mg
EUR 273
Goat anti-Human IgG Fc, F(ab)'2 Fragment, min, cross-reactivity to Human IgA/IgM, Bovine, Horse, Mouse, Rabbit Serum
AS16-3350
Agrisera AB
0,5 mg
EUR 216
Goat anti-Mouse IgG (H&L), F(ab)'2 Fragment, min, cross-reactivity to bovine, goat, human, rabbit, or rat IgG
AS16-3459
Agrisera AB
1,0 mg
EUR 284
Goat anti-Rabbit IgG (H&L), F(ab)'2 fragment, FITC conjugated, min, cross-reactivity to bovin, human, mouse IgG/serum
AS10-1042
Agrisera AB
0,5 mg
EUR 233
Goat anti-Rabbit IgG (H&L), F(ab)'2 fragment, TRITC conjugated, min, cross-reactivity to bovine,human, mouse IgG/serum
AS10-1059
Agrisera AB
0,5 mg
EUR 233
Rabbit anti-Goat IgG (H&L), F(ab)'2 fragment, Affinity purified, Unconjugated, min, cross-reactivity to human, mouse,Rat IgG
AS10-1077
Agrisera AB
1 mg
EUR 246
Goat anti-Rabbit IgG (H&L), F(ab)'2 fragment, HRP conjugated, min, cross-reactivity to bovine,human, mouse IgG/serum
AS10-1146
Agrisera AB
0,5 mg
EUR 233
Goat anti-Rabbit IgG (H&L), F(ab)'2 fragment, Biotin conjugated, min, cross-reactivity to bovine,human, mouse IgG/serum
AS10-1153
Agrisera AB
0,5 mg
EUR 233
Goat anti-Rat IgG (H&L), F(ab)'2 fragment, DyLight® 488 conjugated, min, cross-reactivity to human, mouse lgG
AS10-1217
Agrisera AB
0,5 mg
EUR 259
Goat anti-Human IgG (H&L), F(ab)'2 fragment, Affinity purified, Unconjugated, min, cross-reactivity to bovine/mouse/rabbit serum
AS10-780
Agrisera AB
1 mg
EUR 233
Goat anti-Rat IgG (H&L), F(ab)'2 fragment, DyLight® 550 conjugated, min, cross-reactivity to human, mouse lgG
AS12-1980
Agrisera AB
0,5 mg
EUR 246
Goat anti-Human IgG Fc, F(ab)'2 Fragment, min, cross-reactivity to bovine, horse, mouse or rabbit serum proteins, mouse IgG1
AS16-3356
Agrisera AB
1,0 mg
EUR 238
Goat anti-Mouse IgG (H&L), F(ab)'2 Fragment, min, cross-reactivity to bovine, horse, human, pig or rabbit serum protein
AS16-3461
Agrisera AB
1,0 mg
EUR 252
Goat anti-Rabbit IgG (H&L), F(ab)'2 fragment, Affinity purified, Unconjugated, min, cross-reactivity to bovine, human, mouse IgG/serum
AS10-982
Agrisera AB
1 mg
EUR 190
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, DyLight® 800 conjugated, min, cross-reactivity to human IgG or serum proteins
AS12-2436
Agrisera AB
0,5 mg
EUR 220
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, ALP conjugated, min, cross-reactivity to bovine, goat, human, rabbit, or rat IgG
AS16-3441
Agrisera AB
0,5 mg
EUR 264
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, Biotin conjugated, min, cross-reactivity to bovine, goat, human, rabbit, or rat IgG
AS16-3445
Agrisera AB
0,5 mg
EUR 300
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, FITC conjugated, min, cross-reactivity to bovine, goat, human, rabbit, or rat IgG
AS16-3452
Agrisera AB
0,5 mg
EUR 284
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, HRP conjugated, min, cross-reactivity to bovine, goat, human, rabbit, or rat IgG
AS16-3456
Agrisera AB
0,5 mg
EUR 300
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, TRITC conjugated, min, cross-reactivity to bovine, goat, human, rabbit, or rat IgG
AS16-3468
Agrisera AB
0,5 mg
EUR 284
Goat anti-Rabbit IgG (H&L), F(ab)'2 Fragment, min, cross-reactivity to non-immunoglobulin rabbit serum proteins and human serum proteins
AS16-3530
Agrisera AB
1,0 mg
EUR 203
Goat anti-Rabbit IgG (H&L), F(ab)'2 fragment, ALP (alkaline phosphatase) conjugated, min, cross-reactivity to bovine,human, mouse IgG/serum
AS10-1017
Agrisera AB
0,5 mg
EUR 233
Goat anti-Human IgG Fc, F(ab)'2 Fragment, FITC conjugated, min, cross-reactivity to bovine, horse, mouse or rabbit serum proteins, mouse IgG1
AS16-3354
Agrisera AB
0,5 mg
EUR 238
Goat anti-Human IgG Fc, F(ab)'2 Fragment, HRP conjugated, min, cross-reactivity to bovine, horse, mouse or rabbit serum proteins, mouse IgG1
AS16-3355
Agrisera AB
0,5 mg
EUR 245
Goat anti-Human IgG Fc, F(ab)'2 Fragment, TRITC conjugated, min, cross-reactivity to bovine, horse, mouse or rabbit serum proteins, mouse IgG1
AS16-3358
Agrisera AB
0,5 mg
EUR 275
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, ALP conjugated min, cross-reactivity to bovine, horse, human, pig or rabbit serum protein
AS16-3440
Agrisera AB
0,5 mg
EUR 257
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, Biotin-conjugated, min, cross-reactivity to bovine, horse, human, pig or rabbit serum protein
AS16-3462
Agrisera AB
0,5 mg
EUR 238
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, FITC conjugated, min, cross-reactivity to bovine, horse, human, pig or rabbit serum protein
AS16-3463
Agrisera AB
0,5 mg
EUR 214
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, HRP conjugated, min, cross-reactivity to bovine, horse, human, pig or rabbit serum protein
AS16-3464
Agrisera AB
0,5 mg
EUR 183
Goat anti-Mouse IgG (H&L), F(ab)'2 fragment, TRITC conjugated, min, cross-reactivity to bovine, horse, human, pig or rabbit serum protein
AS16-3465
Agrisera AB
0,5 mg
EUR 214
Goat anti-Rabbit IgG (H&L), F(ab)'2 fragment, DyLight® 594 conjugated, min, cross-reactivity to bovine, human, or Mouse lgG or serum proteins
AS12-2083
Agrisera AB
0,5 mg
EUR 206
Persistent inflammation is a complication associated with many diseases of the eye. Changes in ocular vascular disease response can strengthen and contribute to vision loss by affecting the delivery of leukocytes with the eyes, blood vessels leak, and perfusion. Here, we report the anti-inflammatory activity for AXT107, non-RGD, 20-mer αvβ3 and α5β1 integrin binding peptide that blocks vascular endothelial growth factor (VEGF) -signaling and activates the tyrosine kinase with immunoglobulin and EGF-like domain 2 (Tie2 ) using ligands normally inhibitory angiopoietin 2 (Ang2). Tumor necrosis factor α (TNF), a central mediator of inflammation, Ang2 induces the release of endothelial cells to increase the stimulation of inflammation and leakage of blood vessels
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