Toll-Like Receptor 4 (TLR4)/Opioid Receptor Pathway Crosstalk and Impact on Opioid Analgesia, Immune Function, and Gastrointestinal Motility

Toll-Like Receptor 4 (TLR4)/Opioid Receptor Pathway Crosstalk and Impact on Opioid Analgesia, Immune Function, and Gastrointestinal Motility

Toll-like receptor 4 (TLR4) recognizes exogenous pathogen associated molecular patterns (PAMPs) and endogenous danger associated molecular patterns (muffle) and the initiation of the innate immune response. opioid receptors (μ, δ, and κ) activates the G-protein inhibition and relieve pain. This review summarizes the following types TLR4 / opioid receptor crosstalk pathways: (a) Opioid receptor agonist non-stereoselectively activates TLR4 signaling pathway in central nervous system (CNS), in the absence of lipopolysaccharide (LPS).

Opioids bind to TLR4, in a way consistent with LPS activates TLR4 signaling, which leads to nuclear factor kappa-light-chain-enhancer activated B cells (NF-kB) expression and production of pro-inflammatory cytokine tumor necrosis factor (TNF) -α , interleukin (IL) -1β, and IL-6. (B) Opioid receptor agonists inhibit LPS-induced TLR4 signaling pathway in the peripheral immune cells. Opioids are operating as pro-inflammatory cytokines, resulting in nerve inflammation in the CNS, but they mediate the immunosuppressive effects in the peripheral immune system.

It is clear that the TLR4 / opioid receptor crosstalk pathways vary depending on cell type and stimulus activates. (C) Both TLR4 and opioid receptor pathway activates mitogen-activated protein kinase (MAPK) pathway. This crosstalk is located downstream of TLR4 and opioid receptor signaling pathway. In addition, the classical opioid receptors can also produce pro-inflammatory effects in the CNS through the MAPK signaling and induces neuroinflammation. (D) agonist opioid receptor induces production of high mobility box group 1 (HMGBcellular (neuron-to-glia or glia-to-neuron) interactions.

This review also summarizes the potential effects of TLR4 / opioid receptor pathway crosstalk on analgesia opioids, immune function, and gastrointestinal motility. opioid non-stereoselectively activate the pathway TLR4, and together with the next release of pro-inflammatory cytokines such as IL-1 by glia, TLR4 signifies the initiation of immune middle of the response signal and modify opioid pharmacodynamics.

Toll-Like Receptor 4 (TLR4)/Opioid Receptor Pathway Crosstalk and Impact on Opioid Analgesia, Immune Function, and Gastrointestinal Motility
Toll-Like Receptor 4 (TLR4)/Opioid Receptor Pathway Crosstalk and Impact on Opioid Analgesia, Immune Function, and Gastrointestinal Motility

The. WET neuropathic pain HMGBof to explained the morphine-induced sensitization persistent, positive feedback has been proposed, this involves a morphine-induced reinforced the initial release of IL-1β and release of aggravated subsequent damping, which increases activation of TLR4 and purinergic receptors P2X7R. opioid receptors (μ, δ, and κ) agonists are involved in many aspects of immunosuppression. The intracellular TLR4 / opioi d receptor signaling crosstalk pathway induces the formation of β-Arr estin-2 / TNF receptor-associated factor 6 (TRAF6) complex, which contributes to morphine-induced inhibition of LPS-induced TNF-α secretion in mast cells. A possible molecular mechanism is that TLR4 pathway was initially triggers the formation of β-Arrestin-2 / TRAF6 complex, which is reinforced by the opioid receptor signaling, indicates that β-Arrestin-2 acts as a functional component of TLR4 pathway.

NFκB-p105/p50 (Ab-893) Antibody

21018-50ul 50ul
EUR 224.4

NFκB-p105 (Ab-893) Conjugated Antibody

C21018 100ul
EUR 476.4

anti-NFκB-p105/p50 (Ab-893)

LF-PA20323 100 ul
EUR 400.8
Description: Rabbit polyclonal to NFκB-p105/p50

NFκB-p105/p50 (Ab-893) Antibody

E021018-1 50μg/50μl
EUR 100
Description: Available in various conjugation types.

NFκB-p105/p50 (Ab-893) Antibody

E021018-2 100μg/100μl
EUR 170
Description: Available in various conjugation types.

NF-κB p105/p50 (Ab-893) Antibody

E11-7167B 100μg/100μl
EUR 225
Description: Available in various conjugation types.

Polyclonal MVP / VAULT1 Antibody (aa878-893)

APR02315G 0.05mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human MVP / VAULT1 (aa878-893). This antibody is tested and proven to work in the following applications:

Recombinant Salmonella infB Protein (aa 1-893)

VAng-Wyb0495-inquire inquire Ask for price
Description: Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980) Translation initiation factor IF-2, recombinant protein.

Recombinant Clostridium Botulinum CLJ_B0017 Protein (aa 1-893)

VAng-Lsx8075-1mgEcoli 1 mg (E. coli)
EUR 9846
Description: Clostridium Botulinum (strain 657 / Type Ba4) UPF0182 protein CLJ_B0017, recombinant protein.

Recombinant Clostridium Botulinum CLK_3152 Protein (aa 1-893)

VAng-Lsx8102-1mgEcoli 1 mg (E. coli)
EUR 9846
Description: Clostridium Botulinum (strain Loch Maree / Type A3) UPF0182 protein CLK_3152, recombinant protein.

Recombinant Clostridium Botulinum CLM_0018 Protein (aa 1-893)

VAng-Lsx8112-1mgEcoli 1 mg (E. coli)
EUR 9846
Description: Clostridium Botulinum (strain Kyoto / Type A2) UPF0182 protein CLM_0018, recombinant protein.

Recombinant Clostridium Botulinum CLB_0018 Protein (aa 1-893)

VAng-Lsx8022-1mgEcoli 1 mg (E. coli)
EUR 9846
Description: Clostridium Botulinum (strain ATCC 19397 / Type A) UPF0182 protein CLB_0018, recombinant protein.

Recombinant Clostridium Botulinum CLD_0809 Protein (aa 1-893)

VAng-Lsx8043-1mgEcoli 1 mg (E. coli)
EUR 9846
Description: Clostridium Botulinum (strain Okra / Type B1) UPF0182 protein CLD_0809, recombinant protein.

Activin AB

PR15011 5 ug
EUR 577.2

Soyasaponin Ab

HY-N3026 5mg
EUR 338.4

AB-423

HY-112142 100mg
EUR 2469.6

AB-MECA

HY-19365 5mg
EUR 456

AB-680

HY-125286 10mg
EUR 2126.4

Thyroid Ab/ Rat Thyroid Ab ELISA Kit

ELA-E0844r 96 Tests
EUR 1063.2

GNRHR-Ab/ Rat GNRHR- Ab ELISA Kit

ELA-E0962r 96 Tests
EUR 1063.2

MAG Ab/ Rat MAG Ab ELISA Kit

ELA-E0995r 96 Tests
EUR 1063.2

DNP-Ab/ Rat DNP- Ab ELISA Kit

ELA-E1122r 96 Tests
EUR 1063.2

ENA-Ab/ Rat ENA- Ab ELISA Kit

ELA-E1124r 96 Tests
EUR 1063.2

RNP-Ab/ Rat RNP- Ab ELISA Kit

ELA-E1129r 96 Tests
EUR 1063.2

PDGF-AB/ Rat PDGF- AB ELISA Kit

ELA-E0112r 96 Tests
EUR 1063.2

MBP-Ab/ Rat MBP- Ab ELISA Kit

ELA-E0170r 96 Tests
EUR 1063.2

MC Ab/ Rat MC Ab ELISA Kit

ELA-E0390r 96 Tests
EUR 1063.2

TPO-Ab/ Rat TPO- Ab ELISA Kit

ELA-E0442r 96 Tests
EUR 1063.2

Mouse ACV-AB(Activin AB) ELISA Kit

EM0312 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Mus ;Sensitivity: 0.094 ng/ml

Rat Activin AB,ACV-AB ELISA Kit

SL1432Ra - Ask for price

Camel Theileria Ab,Thi-Ab ELISA Kit

SL0060Cm - Ask for price

Human Brucella Antibody Ab(Brucella-Ab)ELISA Kit

SL3349Hu 96 Tests
EUR 468

Camel Brucella Antibody Ab(Brucella-Ab)ELISA Kit

SL0041Cm - Ask for price

Human TG-ab(anti-Thyroglobulin Ab) ELISA Kit

ELK9250-48T 48T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Human TG-Ab protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TG-Ab. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human TG-Ab in the samples is then determined by comparing the OD of the samples to the standard curve.

Human TG-ab(anti-Thyroglobulin Ab) ELISA Kit

ELK9250-96T 96T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Human TG-Ab protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TG-Ab. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human TG-Ab in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat TG-ab(anti-Thyroglobulin Ab) ELISA Kit

ELK8353-48T 48T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Rat TG-Ab protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat TG-Ab. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat TG-Ab in the samples is then determined by comparing the OD of the samples to the standard curve.

Rat TG-ab(anti-Thyroglobulin Ab) ELISA Kit

ELK8353-96T 96T Ask for price
Description: This assay employs the competitive inhibition enzyme immunoassay technique. The microtiter plate provided in this kit has been pre-coated with Rat TG-Ab protein. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat TG-Ab. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Rat TG-Ab in the samples is then determined by comparing the OD of the samples to the standard curve.

PDGF AB protein

30R-2610 10 ug
EUR 430.8
Description: Purified recombinant Human PDGF AB protein

PDGF AB protein

30R-AP003 10 ug
EUR 327.6
Description: Purified recombinant Human PDGF AB protein

AB-Pinaca Antibody

abx023942-1mg 1 mg
EUR 744

AB-Pinaca Antibody

abx023943-1mg 1 mg
EUR 744

NGAL (Capture Ab)

20-abx019240
  • EUR 176.40
  • EUR 777.60
  • EUR 260.40
  • EUR 493.20
  • EUR 126.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50 ug

NGAL (Capture Ab)

20-abx019241
  • EUR 176.40
  • EUR 777.60
  • EUR 493.20
  • 100 ug
  • 1 mg
  • 500 ug

NGAL (Detection Ab)

abx019242-100ug 100 ug
EUR 777.6

Apoa5 (ab) Antibody

BF0615 200ul
EUR 540

rHu PDGF-AB

AK8282-0002 2µg Ask for price

rHu PDGF-AB

AK8282-0010 10µg Ask for price

rHu PDGF-AB

AK8282-0100 100µg Ask for price

rHu PDGF-AB

AK8282-1000 1mg Ask for price

Elk-1 Ab

3387-100 each
EUR 405.6

AB-2950 MPEC

351201 5unit
EUR 334.8
Description: Super oxide(O2) reaction system L ight Emittingreagent

AB-2960 BactoLumix

3512020 2unit
EUR 378
Description: Menadione oxidation-reduction reaction system for probiotic measurement

AB-3000B Cellgraph

3600000 unit
EUR 120

Ab buffer kit

28903059 EACH
EUR 184.8

Apoa5 (ab) Antibody

abx010415-100ul 100 ul
EUR 493.2

Activin AB, CF

PR15011CF 5 ug
EUR 577.2

PDGF - AB Human

PR27062 2 ug
EUR 229.2

Ab Rabbit GluR2*

P40014-100uL 100uL Ask for price

Ab Rabbit MARCKS*

P40017-100uL 100uL Ask for price

Ab MS GluR1*

P80000-100uL 100uL Ask for price

AB-2950 MPEC

3512010 each
EUR 6600

Human Serum AB

SC00B14 100 ml
EUR 434.4

Apoa5 (ab) Antibody

E10-20006 100μg/100μl
EUR 225
Description: Available in various conjugation types.

SAV Ab Magbeads

E2790053 100ul
EUR 225
Description: Available in various conjugation types.

SAV Ab Magbeads

E2790054 100ul
EUR 225
Description: Available in various conjugation types.

CD2 Ab Magbeads

E601AB001 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD3 Ab Magbeads

E601AB002 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD4 Ab Magbeads

E601AB003 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD14 Ab Magbeads

E601AB005 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD15 Ab Magbeads

E601AB006 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD19 Ab Magbeads

E601AB007 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD20 Ab Magbeads

E601AB008 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD25 Ab Magbeads

E601AB009 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD34 Ab Magbeads

E601AB010 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD44 Ab Magbeads

E601AB011 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD45 Ab Magbeads

E601AB012 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CD63M Ab Magbeads

E601AB014 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

HSP70 Ab Magbeads

E601AB016 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

EPCAM Ab Magbeads

E601AB017 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CEA Ab Magbeads

E602AB004 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

AFP Ab Magbeads

E602AB005 ~2X109 cells, 1ml
EUR 595
Description: Available in various conjugation types.

PSA Ab Magbeads

E602AB006 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

NSE Ab Magbeads

E602AB008 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CK19 Ab Magbeads

E602AB010 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CA199 Ab Magbeads

E602AB012 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CA242 Ab Magbeads

E602AB013 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CA724 Ab Magbeads

E602AB014 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CA125 Ab Magbeads

E602AB015 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

TPA Ab Magbeads

E602AB016 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

SCCA Ab Magbeads

E602AB017 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

Ferritin Ab Magbeads

E602AB018 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CA50 Ab Magbeads

E602AB019 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CK8 Ab Magbeads

E602AB020 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CK18 Ab Magbeads

E602AB021 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CK20 Ab Magbeads

E602AB022 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

HE4 Ab Magbeads

E602AB027 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

GPC1 Ab Magbeads

E602AB030 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

SUPAR Ab Magbeads

E602AB031 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CKMB Ab Magbeads

E603AB001 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CTNI Ab Magbeads

E603AB004 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

CRP Ab Magbeads

E603AB006 ~2X109 cells, 1ml
EUR 395
Description: Available in various conjugation types.

H.Pylori Ab test

04FK10 30 tests/kit
EUR 71.5

Chagas Ab test

49FK10 25 tests/kit
EUR 55

ELISA kit for Mouse ACV-AB (Activin AB)  Kit

E-EL-M2660 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Mouse ACV-AB (Activin AB)  Kit in samples from Serum, Plasma, Cell supernatant

n-DNA-Ab/ Rat n- DNA- Ab ELISA Kit

ELA-E1126r 96 Tests
EUR 1063.2

Sc1-70-Ab/ Rat Sc1- 70- Ab ELISA Kit

ELA-E1131r 96 Tests
EUR 1063.2

IFN-Gamma ab/ Rat IFN- Gamma ab ELISA Kit

ELA-E1716r 96 Tests
EUR 1063.2

G-CSF ab/ Rat G- CSF ab ELISA Kit

ELA-E1717r 96 Tests
EUR 1063.2

ACV-AB ELISA Kit| Mouse Activin AB ELISA Kit

EF012990 96 Tests
EUR 826.8

Feline Immunodefiency Virus Ab (FIV Ab) Rapid Test Kit

HG039 10 Tests/Kit
EUR 21
Description: Contents: (1) 10 Tests/Kit   (cassette,disposable dropper,desiccant) (2) 10 Assay buffer tubes (3) 10 Sterile swabs (4) 1 Instruction manual

Human  Anti Amyloid beta Ab (Abeta-Ab)ELISA Kit

SL3770Hu 96 Tests
EUR 468

Human Platelet Derived Growth Factor AB (PDGF-AB) CLIA Kit

abx197488-96tests 96 tests
EUR 990

Rat Platelet-Derived Growth Factor AB (PDGF-AB) CLIA Kit

abx197512-96tests 96 tests
EUR 990

Human Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

201-12-0138 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Pig Platelet-Derived Growth Factor AB (PDGF-AB) ELISA kit

CSB-EQ027978PI-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Pig Platelet-Derived Growth Factor AB (PDGF-AB) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Pig Platelet-Derived Growth Factor AB (PDGF-AB) ELISA kit

1-CSB-EQ027978PI
  • EUR 1080.00
  • EUR 6571.20
  • EUR 3480.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Pig Platelet-Derived Growth Factor AB (PDGF-AB) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

CN-03255H1 96T
EUR 560.4

Human Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

CN-03255H2 48T
EUR 379.2

Rat Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

CN-01590R1 96T
EUR 548.4

Rat Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

CN-01590R2 48T
EUR 367.2

Mouse Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

CN-02423M1 96T
EUR 548.4

Mouse Platelet-Derived Growth Factor AB,PDGF-AB ELISA kit

CN-02423M2 48T
EUR 367.2

Human Platelet-Derived Growth Factor AB, PDGF-AB ELISA kit

CSB-E04701h-24T 1 plate of 24 wells
EUR 198
Description: Quantitative sandwich ELISA kit for measuring Human Platelet-Derived Growth Factor AB, PDGF-AB in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Platelet-Derived Growth Factor AB, PDGF-AB ELISA kit

1-CSB-E04701h
  • EUR 867.60
  • EUR 5859.60
  • EUR 3109.20
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitative sandwich ELISA kit for measuring Human Platelet-Derived Growth Factor AB, PDGF-AB in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat Platelet-Derived Growth Factor AB, PDGF-AB ELISA kit

CSB-E04703r-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Rat Platelet-Derived Growth Factor AB, PDGF-AB in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rat Platelet-Derived Growth Factor AB, PDGF-AB ELISA kit

1-CSB-E04703r
  • EUR 843.60
  • EUR 5811.60
  • EUR 3084.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rat Platelet-Derived Growth Factor AB, PDGF-AB in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rabbit Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit

CSB-E15910Rb-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Rabbit Platelet-Derived Growth Factor AB (PDGF-AB) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Rabbit Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit

1-CSB-E15910Rb
  • EUR 843.60
  • EUR 5811.60
  • EUR 3084.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Rabbit Platelet-Derived Growth Factor AB(PDGF-AB) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Rat PDGF-AB(Platelet-Derived Growth Factor AB) ELISA Kit

ER0056 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 4.688pg/ml

Rabbit PDGF-AB(Platelet Derived Growth Factor AB) ELISA Kit

ERB0095 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rabbit;Sensitivity: 0.938 ng/ml

Rat Platelet-Derived Growth Factor AB(PDGF-AB)ELISA Kit

GA-E0700RT-48T 48T
EUR 447.6


Persistent inflammation is a complication associated with many diseases of the eye. Changes in ocular vascular disease response can strengthen and contribute to vision loss by affecting the delivery of leukocytes with the eyes, blood vessels leak, and perfusion. Here, we report the anti-inflammatory activity for AXT107, non-RGD, 20-mer αvβ3 and α5β1 integrin binding peptide that blocks vascular endothelial growth factor (VEGF) -signaling and activates the tyrosine kinase with immunoglobulin and EGF-like domain 2 (Tie2 ) using ligands normally inhibitory angiopoietin 2 (Ang2). Tumor necrosis factor α (TNF), a central mediator of inflammation, Ang2 induces the release of endothelial cells to increase the stimulation of inflammation and leakage of blood vessels

Tony

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